Post-doctoral Position in Gene Regulatory Network Engineering

Updated: 14 days ago
Deadline:


Job Type / Workload
Academic: Post Doc Position / Senior Scientist 100%
Workload
0 weekly jours
Industry
Education / Culture
Functional Area
Academic Research / Teaching
Salary
CHF 0 /
Entry date
November 28, 2019
immediately
Region
Switzerland - Western Part & Valais
< 1 / >
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Description:

The Laboratory of Biological Network Characterization is looking to hire a post-doctoral researcher in the area of gene regulatory network and promoter engineering. 

The project will focus on cis-regulation of gene regulatory networks in vivo in the model organism S. cerevisiae. We plan to decipher the importance of various transcription factor biophysical properties on their ability to regulate target genes. To do so we will establish large libraries of synthetic promoters and gene regulatory networks in combination with fully characterized synthetic transcription factors. The project will make us of state-of-the-art genome engineering technologies as well as microfluidic platforms for high-throughput single cell characterization.

This position is supported by a SNSF Sinergia grant and the work will be conducted in close collaboration with the laboratories of Prof. David Suter (EPFL) and Prof. Erik van Nimwegen (University of Basel). Our laboratory is furthermore supported by an ERC Consolidator Grant (RetroNets) focused on reverse engineering yeast gene regulatory networks.

Requirements:

Candidates should hold a PhD degree in Biochemistry, Bioengineering, Chemical Engineering, Chemistry, or related field. The candidate should have a strong background in protein biochemistry, molecular engineering, or synthetic biology, although other backgrounds may also be considered. Prior experience with S. cerevisiae genetics is highly desired.

Candidates should send their curriculum vitae, a cover letter, and the contact information for 3 references to:

Prof. Sebastian Maerkl

Email: sebastian.maerkl@epfl.ch

Evaluation will begin immediately. The position is expected to be filled in Q1/Q2 of 2020.


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synthetic biologytranscriptional regulationtranscription factor biophysicsmicrofluidics
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