Ph.D. Position in Transcription Factor Engineering

Updated: about 2 months ago
Deadline:


Job Type / Workload
Academic: PhD Position 100%
Workload
0 weekly jours
Industry
Education / Culture
Functional Area
Academic Research / Teaching
Salary
CHF 0 /
Entry date
November 28, 2019
immediately
Region
Switzerland - Western Part & Valais
< 1 / >
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Description:

The Laboratory of Biological Network Characterization is looking to hire a PhD student in the area of transcription factor engineering and characterization.

The project will involve engineering and comprehensive biochemical characterization of transcription factors and their deployment in vivo and in vitro. This work will provide insights into the importance of various transcription factor biophysical properties on their ability to regulate complex gene regulatory networks as well as improve our ability to engineer transcriptional regulators and corresponding gene regulatory networks. The project will make use of state-of-the-art gene synthesis approaches, cell-free protein synthesis, and high-throughput microfluidic platforms for biochemical characterization.

This position is supported by a SNSF Sinergia grant and the work will be conducted in close collaboration with the laboratories of Prof. David Suter (EPFL) and Prof. Erik van Nimwegen (University of Basel). Our laboratory is furthermore supported by an ERC Consolidator Grant (RetroNets) focused on reverse engineering yeast gene regulatory networks.

Requirements:

Candidates should hold a Master’s degree in Biochemistry, Bioengineering, Chemical Engineering, Chemistry, or related field.

Candidates should send their curriculum vitae and a cover letter to:

Prof. Sebastian Maerkl

Email: sebastian.maerkl@epfl.ch

Evaluation will begin immediately and proceed until the position has been filled. Selected candidates will be asked to submit an official application package to the EDBB doctoral program for the April 15th application deadline.


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microfluidicssynthetic biologytranscriptional regulationtranscription factor biophysics
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