The Biozentrum of the University of Basel is one of the leading life sciences institutes in the world. It consists of 30 groups and 500 employees that research how molecules and cells create life, spanning the scale from atom to organism. Founded in 1971, the Biozentrum has been the birthplace of many fundamental discoveries in biology and medicine, spawning several Nobel Laureates.
In Prof. Torsten Schwede's group, we use computational methods to model protein structures, characterise protein-ligand interactions, and explore the effects of mutations on protein structure and function. We also explore the application of AI methods to characterise the viral and dark proteome, and to automate areas of discovery and design of novel therapeutics.
Within the SIB Swiss Institute of Bioinformatics, we develop SWISS-MODEL (https://swissmodel.expasy.org ), a widely used web-based platform for generating high-accuracy 3D models of protein structures and complexes for application in life sciences.
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