Wir bieten Ihnen
- You will have access to state-of-the-art research equipment in metabolomics, cell biology, time-lapse microscopy.
- You will work in a dynamic and highly interdisciplinary team including computer scientists and experimentalists.
- You will be involved in cross-disciplinary collaborations and have training opportunities to further develop and grow your scientific interests.
- Opportunity to work in close contact with other basic- and clinical-research groups at the Department of Biomedicine in Basel
- Support from highly competent, experienced team members and potential to lead projects with a high degree of academic freedom
Key References
Ortmayr, K. and Zampieri M. "Sorting-free metabolic profiling uncovers the vulnerability of fatty acid β-oxidation in in vitro quiescence models". To appear in Molecular Systems Biology 2022
Anglada-Girotto, M., Handschin, G., Ortmayr, K. et al. Combining CRISPRi and metabolomics for functional annotation of compound libraries. Nat Chem Biol 18, 482–491 (2022).
Ortmayr, K., Dubuis, S. & Zampieri, M. Metabolic profiling of cancer cells reveals genome-wide crosstalk between transcriptional regulators and metabolism. Nat Commun 10, 1841 (2019).
Dubuis, S., Ortmayr, K. & Zampieri, M. A framework for large-scale metabolome drug profiling links coenzyme A metabolism to the toxicity of anti-cancer drug dichloroacetate. Commun Biol 1, 101 (2018).
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