PhD Position for Synthetic Biology-Inspired Therapies

100%, Basel, fixed-term

The Biotechnology and Bioengineering group directed by Prof. Martin Fussenegger at the Department of Biosystems Science and Engineering (D-BSSE), in Basel is recruiting a PhD candidate for research projects in the fields of personalized medicine and bioelectronics.

The D-BSSE is the first truly interdisciplinary research unit of ETH Zurich where theory, experimental biology and engineering groups team up to foster advances in Systems Biology, Biotechnology and Synthetic Biology. With its headquarters in Basel, Switzerland, the D-BSSE is situated in the heart of the Biovalley, a tri-national region hosting 40% of the global life science industry including several pharma giants, which provides a unique environment for high-leverage translational research.

Project background

Our group uses state-of-the-art Synthetic Biology principles to engineer human cells and develop cell-based therapies for the treatment of cancer as well as metabolic, neurodegenerative, autoimmune and infectious diseases. Please consult our webpage and published work for further information.

Job description

The projects will combine basic and translational research to develop novel synthetic biology-inspired principles. Rational programming the behavior of human cells will shape future biomedical applications. This may include the design of novel biosensors, gene switches and genetic closed-loop circuits, the synthesis of novel chemical structures to interface and actuate cellular activities or to design programmable cellular implantable devices.

Your profile

• You are exceptionally motivated to bridge basic and translational research in cell biology and synthetic biology.
• Strong skills in standard molecular and cell biology techniques and the cultivation and engineering of primary human cells and mammalian cell lines are a prerequisite.
• We expect an outstanding study record as well as the ambition to pursue an academic, industrial R&D career or to initiate start-up activities.

Your workplace

Your workplace

We offer

ETH Zurich is a family-friendly employer with excellent working conditions. You can look forward to an exciting working environment, cultural diversity and attractive offers and benefits.

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We value diversity

In line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected. Visit our

Equal Opportunities and Diversity website

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Curious? So are we.

We look forward to receiving your online application including:

• CV
• full study record
• publication list
• a motivation letter
• two letters of recommendation (if available)

​​​​​​Please note that we exclusively accept applications submitted through our online application portal. Applications via email or postal services will not be considered.
For additional questions please contact Professor Martin Fussenegger by mail: martin.fussenegger@bsse.ethz.ch (no applications).

About ETH Zürich

ETH Zurich is one of the world’s leading universities specialising in science and technology. We are renowned for our excellent education, cutting-edge fundamental research and direct transfer of new knowledge into society. Over 30,000 people from more than 120 countries find our university to be a place that promotes independent thinking and an environment that inspires excellence. Located in the heart of Europe, yet forging connections all over the world, we work together to develop solutions for the global challenges of today and tomorrow.