PhD in Chemical Biology/Peptide Chemistry, University of Bern

A graduate student positions are open starting April 2022 to carry out a Ph.D. thesis in chemical biology. Applicants must hold a Master’s degree in Chemistry of Biochemistry and have interest to work in an interdisciplinary environment. The research projects focus on the computational design, synthesis, testing and mechanistic studies of bioactive peptides, cyclic peptides and peptide dendrimers. Recent publications of the group on this topic:

- S. Zamolo et al. Transfecting tissue models with CRISPR/Cas9 plasmid DNA using peptide dendrimer. Chem. Commun. 2020, https://doi.org/10.1039/D0CC04750C

- T Siriwardena et al. Stereorandomization as a Method to Probe Peptide Bioactivity. ACS Cent. Sci. 2021, https://doi.org/10.1021/acscentsci.0c01135

- A. Capecchi et al., Machine learning designs non-hemolytic antimicrobial peptides. Chem. Sci. 2021, https://doi.org/10.1039/D1SC01713F

- S. Baeriswyl et al. A mixed chirality α-helix in a stapled bicyclic and a linear antimicrobial peptide revealed by X-ray crystallography. RSC Chem. Biol. 2021, https://doi.org/10.1039/D1CB00124H

- D. Erzina et al. An Immunomodulatory Peptide Dendrimer Inspired from Glatiramer Acetate. Angew. Chem. Int. Ed. 2021, https://doi.org/10.1002/anie.202113562

- A. Capecchi and J.-L. Reymond. Peptides in chemical space. Med. Drug Discovery 2021, https://doi.org/10.1016/j.medidd.2021.100081