PhD student in Biophysics (A)

Ref. No. SU FV-0202-23

at the Department of Biochemistry and Biophysics . (Closing date: 21 February 2023.) Prolonged application time - New closing date: 28 Febrary 2023

SciLifeLab (SciLifeLab ) is a national center for molecular biosciences with focus on health and environmental research. The center combines frontline technical expertise with advanced knowledge of translational medicine and molecular bioscience. SciLifeLab is a national resource hosted by Karolinska Institutet, KTH Royal Institute of Technology, Stockholm University and Uppsala University. The center also collaborates with several other universities.

The employment will be placed at the Department of biochemistry and biophysics, at Stockholm university.

Project description
Your studies in Biophysics will be in the project: "Investigating T cell activation through the characterization of its molecular landscape with super resolution microscopy”.

Super resolution (SR) encompasses advanced light microscopy techniques which have in common to circumvent the diffraction limit. More concretely, it uniquely enables imaging fluorophores with a resolution ranging from a few nm to 200nm. It provides unprecedented insight into cells’ molecular life and has highlighted the key role played by signaling proteins spatial (re)organization and interactions at the nanoscale. As such SR has opened novel promising avenues of research when it comes to investigating complex cellular processes

Relying on SR, the selected PhD candidate will study the processes behind specific immunity. T cells play an essential role in the buildup of immune responses, and SR provides an outstanding platform to improve our understanding of their activation and overall functioning at the molecular level. The project is highly multidisciplinary, relying on cutting edge imaging techniques to answer fundamental biological issues. We are looking for a PhD candidate with MS Majors in either biology/biophysics/biochemistry. Experience with sample preparation for microscopy is a requirement, super resolution microscopy is a plus.

The Selected PhD candidate will be joining the Computational Microscopy for Cell Biology (CMCB) lab, led by Dr. J. Griffié (https://www.scilifelab.se/researchers/juliette-griffie/ ). The lab will be based at SciLifeLab in Stockholm, a vibrant and dynamic science hub, with a particular focus in multidisciplinary research to study biological systems. The CMCB laboratory aims more specifically at developing cutting-edge data/image analysis strategies to answer fundamental biology questions with advanced light microscopy. The lab’s research scope ranges from studying cells at the molecular level, developing machine learning tools to extract meaningful information from images as well as modelling.

Qualification requirements
In order to meet the general entry requirements, the applicant must have completed a second-cycle degree, completed courses equivalent to at least 240 higher education credits, of which 60 credits must be in the second cycle, or have otherwise acquired equivalent knowledge in Sweden or elsewhere.

In order to meet the specific entry requirements for acceptance in the Biophysics program, the applicant must have passed courses within the first and second cycles of at least 120 credits in Physics or Chemistry and at the second level, courses of at least 60 credits Biophysics, Biochemistry or Physical Chemistry including a 30 credit Degree Project (thesis).

The qualification requirements must be met by the deadline for applications. 

Selection
The selection among the eligible candidates will be based on their capacity to successfully complete the program. Important criteria when assessing this capacity are; documented knowledge and skills in the field of the thesis project, written and oral proficiency in English, the capacity for analytical thinking, the ability to collaborate, as well as creativity, initiative, and independence. The assessment will be based on previous experience and grades, the quality of the degree project, references, relevant experience, interviews, and the candidate’s written motivation for seeking the position. 

Experience with molecular biology techniques such as cloning or mutagenesis and knowledge of Linux commands scripting will be considered as an advantage.

Admission Regulations for Doctoral Studies at Stockholm University are available at: www.su.se/rules and regulations .

Terms of employment
Only a person who will be or has already been admitted to a third-cycle programme may be appointed to a doctoral studentship.

The term of the initial contract may not exceed one year. The employment may be extended for a maximum of two years at a time. However, the total period of employment may not exceed the equivalent of four years of full-time study.

Doctoral students should primarily devote themselves to their own education, but may engage in teaching, research, and administration corresponding to a maximum of 20 % of a full-time position.

Please note that admission decisions cannot be appealed.

Stockholm University strives to be a workplace free from discrimination and with equal opportunities for all.

Contact
For more information, please contact project leader, Associate Professor, Juliette Griffie, [email protected] .

General information about the PhD programs can be given by the Director of Doctoral Studies, Pia Ädelroth, [email protected]  or the Head of the Department, Martin Högbom, [email protected] .

Union representatives
Ingrid Lander (Saco-S), telephone: +46 708 16 26 64, [email protected] , Alejandra Pizarro Carrasco (Fackförbundet ST/Lärarförbundet), telephone: +46 8 16 34 89, [email protected] , [email protected]  (SEKO), and PhD student representative, [email protected] .

Application
Apply for the PhD student position at Stockholm University's recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the advertisement, and that it is submitted before the deadline.

Please include the following information with your application

• Your contact details and personal data
• Your highest degree
• Your language skills
• Contact details for 2–3 references

and, in addition, please include the following documents

• Cover letter
• CV – degrees and other completed courses, work experience and a list of degree projects/theses
• Project proposal/Research proposal describing:
  – why you are interested in the field/project described in the advertisement
  – why and how you wish to complete the project
  – what makes you suitable for the project in question
• Degree certificates and grades confirming that you meet the general and specific entry requirements (no more than 6 files)
• Letters of recommendation (no more than 6 files)
• Degree projects/theses (no more than 6 files).

The instructions for applicants are available at: How to apply for a position .

You are welcome to apply!

Stockholm University contributes to the development of sustainable democratic society through knowledge, enlightenment and the pursuit of truth.

URL to this page
https://www.su.se/english/about-the-university/work-at-su/available-jobs/phd-student-positions-1.507588?rmpage=job&rmjob=19947&rmlang=UK