PhD position on Context-dependency on the fate and ecotoxicological effects of antibiotics and antimicrobial resistance on river sediment

Updated: about 1 month ago
Job Type: FullTime
Deadline: 14 Apr 2024

18 Mar 2024
Job Information
Organisation/Company

University of Gothenburg
Research Field

Environmental science
Researcher Profile

First Stage Researcher (R1)
Country

Sweden
Application Deadline

14 Apr 2024 - 18:00 (Europe/Paris)
Type of Contract

Temporary
Job Status

Full-time
Offer Starting Date

15 Mar 2024
Is the job funded through the EU Research Framework Programme?

HE / MSCA
Marie Curie Grant Agreement Number

101119261
Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

BACKGROUND

This doctoral position is 1 of 10 doctoral positions offered within the he HORIZON Marie Sklodowska-Curie Action (MSCA) Doctoral Network Pharm-ERA : Improving monitoring and Environmental Risk Assessment of PHARMaceuticals, antimicrobial resistance and pathogens from terrestrial to aquatic environments.

Global contamination of soil and aquatic ecosystems by pharmaceutical and microbiological pollutants (such as antimicrobial-resistant microorganisms and/or pathogens) raises severe concerns about impacts on ecosystem health and repercussions on humans and animals. Preserving ecosystems from adverse ecotoxicological effects of pharmaceuticals and their transformation products, and limiting the environmental spread of antimicrobial resistance and pathogens is imperative to reach several UN Sustainable Development Goals as well as the European Green Deal, Water Framework Directive and Biodiversity Strategy for 2030. In this context, the main scientific objective of Pharm-ERA is to develop and implement innovative concepts, methods and strategies to improve the monitoring and assessment of the environmental effects and risks of pharmaceuticals, their transformation products, antimicrobial resistances and pathogens from terrestrial to aquatic environments. The ultimate goal is to provide scientific evidence and expertise to contribute to reducing the environmental spread and impact of these chemical and microbiological contaminants and to preserve microbial diversity and functions across the soil-water-sediment continuum.

By joining Pharm-ERA, you will integrate a high-level interdisciplinary and intersectoral research and training network based on 10 doctoral projects covering scientific disciplines including environmental and analytical chemistry, microbial ecology, ecotoxicology, molecular biology (incl. multi-omics approaches) and chemical fate/effect modelling. Pharm-ERA involves 9 Beneficiaries (including 2 non-academics) and 6 Associated Partners (including 5 non-academics), committed to contribute to research, training, dissemination, communication and exploitation of results targeting end-users such as environmental consultancies and agencies.

DESCRIPTION OF THE PhD PROJECT

Antibiotics and antimicrobial resistance (AMR) pollution in urban rivers receiving waste water treatment plants (WWTP) effluents is common, but their fate, and environmental risk remains poorly studied in river sediment. Context-dependency (ecological abiotic and biotic factors) influences the assembly of natural communities of bacteria and may affect their sensitivity to antibiotics and AMR. This PhD project will provide new knowledge on the interactions between pollutants (residues of antibiotics and AMR) and sediment bacteria, under altered abiotic and biotic contexts: a gradient of microbial diversity, pre-exposure history and/or pollution levels. Experimental studies using natural microbial communities in microcosms facilities and field sampling will be implemented for hypothesis testing. Effects will be quantitatively assessed by linking microbial composition and function using a combination of molecular tools such as metagenomics, quantitative PCR, and eco(tox)logical methods such as nitrogen turnover processes and antibiotics transformation rates.

The PhD student will join the Algal and Microbial Ecotoxicology Lab at the University of Gothenburg (Sweden) and work with experimental testing, environmental microbiology, molecular approaches, microbial functions, and sequencing-based tools. In addition, the PhD student will have hand-on isolation of antibiotics resistance bacteria and antibiotics turnover in collaboration with the Agroécologie Laboratory at INRAE BFC, Dijon (France) and on environmental analytical chemistry in collaboration with IDAEA-CSIC, Barcelona (Spain). Overall this PhD will prepare you to become an environment expert in environmental microbiology, ecotoxicology, community ecology and risk assessment.


Requirements
Research Field
Environmental science
Education Level
Master Degree or equivalent

Skills/Qualifications
  • Knowledge in environmental microbiology, microbial ecology, molecular biology, laboratory work, some bioinformatics, environmental analytical chemistry, academic writing and data analysis
  • Master degree in environmental microbiology, ecotoxicology, aquatic ecology, environmental sciences or similar programs

Specific Requirements
  • MSCA Mobility Rule: researchers must not have resided or carried out their main activity (work, studies, etc.) in the country of the recruiting beneficiary for more than 12 months in the 36 months immediately before their date of recruitment
  • All researchers recruited in a DN must be doctoral candidates (i.e. not already in possession of a doctoral degree at the date of the recruitment)
  • Scientific excellence to fit the PhD project
  • Fluent (oral and written) English skills as the project operates in English language
  • Knowledge of the language of the host country may be considered a merit
  • Team-mindedness

Languages
ENGLISH
Level
Excellent

Research Field
Environmental science

Additional Information
Eligibility criteria
  • MSCA Mobility Rule: researchers must not have resided or carried out their main activity (work, studies, etc.) in the country of the recruiting beneficiary for more than 12 months in the 36 months immediately before their date of recruitment
  • All researchers recruited in a DN must be doctoral candidates (i.e. not already in possession of a doctoral degree at the date of the recruitment

Selection process

How to apply to Pharm-ERA?

  • Select your topic in the PhD offers page & download the detailed offer, please note that it is possible to apply for several offers
     
  • Download application form (here) and fill it indicating all the offers you wish to apply for. Save it with the name "PhD application form - YOUR NAME (first and last)"
     
  • Send your application by email to [email protected] . The title of your email MUST be : Pharm-ERA PhD x, x, x application (x, x, x being the number(s) of the PhD position(s) you want to apply for). Please favor sending documents using a file transfer solution (e.g. wetransfer )
     
  • Be careful to join all documentation required (see list below)
     
  • You will receive an aknowledgment of receipt within the next 2 working days (if it's not the case, send an email to [email protected] )
     
  • DEADLINE for application is April 14th 2024, 6:00 pm french time

  • Additional comments
    • Application form completed
    • Letter of motivation
    • Contact of two reference persons to be contacted by the selection committee (name, relation to the candidate, e-mail address and phone number)
    • CV
    • Complete list of publications and academic works
    • Proof of language proficiencies
    • Proof of master diploma or 2024 registration to master degree

    Website for additional job details

    https://pharm-era.hub.inrae.fr

    Work Location(s)
    Number of offers available
    1
    Company/Institute
    University of Gothenburg
    Country
    Sweden
    City
    Gothenburg
    Geofield


    Where to apply
    Website

    https://pharm-era.hub.inrae.fr/phd-recruitment/how-to-apply

    Contact
    City

    Gothenburg
    Website

    https://pharm-era.hub.inrae.fr
    E-Mail

    [email protected]

    STATUS: EXPIRED

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