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cell division counting in mice and humans to investigate the differentiation of individual stem and progenitor cells. In the longer term, our results will improve understanding of healthy hematopoieisis
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function of these cells, we combine directed differentiation of human pluripotent stem cells, in vitro and in vivo models of human normal and leukemic development, and state-of-the-art epigenomic and
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, senescence, and aging. MAIN RESPONSABILITIES The successful candidate will explore the molecular and epigenetic mechanisms controlling the SIRT7/PAX5 interplay in B-cell differentiation and B-Acute
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