The applicant Is expected to conduct a project focused on the identification of ncRNA species early deregulated in Huntington’s disease (HD) neurodegeneration and understand their involvement in disease evolution. The understanding of how small RNAs, confer neurotoxicity and their possible functional interaction with other pathogenic mechanisms is crucial to develop effective disease-modifying interventions. The candidate will apply a combination of experimental approaches in in vitro and in vivo models and computational methods
Specific objectives and tasks in which the candidate will be involved are: (1) To study the cell-type specificity of ncRNA formation and their correlation with HD progression stages. (2) To determine the molecular mechanisms by which ncRNAs could induce pathogenic disturbances in HD and (3) To investigate the potential use of ncRNA modulators as novel therapeutic targets to HTT-related neurotoxicity
Postdoc & Ph D Student Position In Immunology , University of Basel, Switzerland, 22 days ago
The Finke laboratory (https://biomedizin.unibas.ch/en/research/research-groups/finke-lab/ ) is seeking a highly motivated PhD candidate and an early postdoctoral researcher to investigate tissue-s...
Doctoral (Ph D) Student Position In Targeting Neuroinflammation For Neuroprotection In Glaucoma, Karolinska Institutet, Sweden, 16 days ago
To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of...
Three Ph D Fellowships In Plant Immunity, University of Copenhagen, Denmark, about 23 hours ago
Dept. of Plant and Environmental Sciences invites applicants for PhD fellowships in studies of plant immunity. Start date is Oct. 1, 2022 or as soon as possible thereafter. The projects The projec...
Ph D Fellowship In “Protective Mechanisms Of Selenocyanate In Inflammatory Disease, University of Copenhagen, Denmark, about 23 hours ago
We are offering a PhD fellowship in “Protective mechanisms of selenocyanate in inflammatory disease” commencing 1 October 2022 or as soon as possible hereafter. Our group and research The Departme...
Ph D Project Unraveling The Mechanisms Of Action Of Anabolic Osteoporosis Therapy, Katholieke Universiteit Leuven, Belgium, 1 day ago
With ageing our bones become brittle and prone to fractures, known as osteoporosis. Despite widespread use of therapies blocking bone loss, osteoporosis represents a major public health concern. T...
Ph D Position In Quantitative Cell Biology/Biochemistry (1.0 Fte), University of Groningen, Netherlands, about 8 hours ago
Organisation Founded in 1614, the University of Groningen enjoys an international reputation as a dynamic and innovative centre of higher education offering high-quality teaching and research. Fle...