The Group of Psychiatry, Mental Health and Addictions is seeking a PhD student to apply for competitive grants with experience in statistical analysis to work on neurodevelopmental disorders, including attention deficit and hyperactivity disorder (ADHD).
Neurodevelopmental disorders are highly heritable, comorbid, have substantial diagnostic overlap and share clinical features and genetic etiology. ADHD is one of the most common across lifespan with high functional impact in adults.
The objective of the position is (i) to study clinical trajectories in adults with ADHD (ii) to determine clinical variables associate with treatment response
Group publication related with the project:
1: Cabana-Domínguez J, Soler Artigas M, Arribas L, Alemany S, Vilar-Ribó L, Llonga N, Fadeuilhe C, Corrales M, Richarte V, Ramos-Quiroga JA, Ribasés M. Comprehensive analysis of omics data identifies relevant gene networks for Attention-Deficit/Hyperactivity Disorder (ADHD). Transl Psychiatry. 2022.
2: Rajagopal VM, Duan J, Vilar-Ribó L, Grove J, Zayats T, Ramos-Quiroga JA, Satterstrom FK, Artigas MS, Bybjerg-Grauholm J, Bækvad-Hansen M, Als TD, Rosengren A, Daly MJ, Neale BM, Nordentoft M, Werge T, Mors O, Hougaard DM, Mortensen PB, Ribasés M, Børglum AD, Demontis D. Differences in the genetic architecture of common and rare variants in childhood, persistent and late-diagnosed attention-deficit hyperactivity disorder. Nat Genet. 2022 Aug;54(8):1117-1124.
3: Soler Artigas M, Sánchez-Mora C, Rovira P, Vilar-Ribó L, Ramos-Quiroga JA, Ribasés M. Mendelian randomization analysis for attention deficit/hyperactivity disorder: studying a broad range of exposures and outcomes. Int J Epidemiol. 2022.
4: Demontis D, Walters RK, Rajagopal VM, Waldman ID, Grove J, Als TD, Dalsgaard S, Ribasés M, Bybjerg-Grauholm J, Bækvad-Hansen M, Werge T, Nordentoft M, Mors O, Mortensen PB; ADHD Working Group of the Psychiatric Genomics Consortium (PGC), Cormand B, Hougaard DM, Neale BM, Franke B, Faraone SV, Børglum AD. Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder. Nat Commun. 2021.
Main responsibilities and duties:
The PhD Fellow will work under the supervision of Dr. Josep Antoni Ramos-Quiroga head of the Group of Psychiatry, Mental Health and Addictions at the Vall d’Hebron Research Institute and Dr Vanesa Richarte member of this group.
Responsibilities will include statistical analyses of clinical features on ADHD, manuscript writing, and oral presentations at meetings, consortium calls, and scientific conferences. The candidate will also engage in regular collaborative meetings with teams of scientists locally and internationally, including ECNP ADHD network. There will also be training opportunities for new statistical methods and psychological aproaches, aiming to help the candidate to enhance his/her employability.
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