PhD position - Exploring the frontiers of protein dynamics: from crystallography to ultrafast spectroscopy

12 Feb 2024
Job Information

Organisation/Company

Pavol Jozef Šafárik University in Košice

Research Field

Physics » Biophysics

Researcher Profile

First Stage Researcher (R1)

Country

Slovakia

Application Deadline

15 Apr 2024 - 00:00 (Europe/Bratislava)

Type of Contract

Temporary

Job Status

Full-time

Hours Per Week

37,5

Offer Starting Date

1 Sep 2024

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

Annotation of the dissertation topic:

Join our cutting-edge research project aimed at unraveling the intricate world of protein structures and dynamics. This PhD opportunity will immerse you in the fascinating realm of protein crystallography and advanced spectroscopic techniques. You will be at the forefront of employing state-of-the-art methodologies to delve into protein-ligand interactions, protein quakes, and crucial enzymatic processes like proton and electron transfers. As a PhD candidate, you will be instrumental in conducting these sophisticated experiments, analyzing data, and contributing to the field's knowledge. This project offers a unique interdisciplinary and international experience between Košice(SK)•Prague(CZ)•Paris, (FR), bridging the gap between structural biology, biophysics, and chemistry. Your research could pave the way for groundbreaking advancements in understanding protein mechanisms, potentially leading to novel therapeutic approaches.

Project goals:

1) Determine the three-dimensional structures of novel protein domains, including new chaperone domains of Hsp70.

2) Investigate human pathological immunoglobulin light chains in complex with emerging therapeutics.

3) Apply ultrafast optical spectroscopies and time-resolved X-ray techniques to study enzyme catalysis and other dynamic processes.

Requirements

Research Field

Physics » Biophysics

Education Level

Master Degree or equivalent

Level

Excellent

Additional Information
Work Location(s)

Number of offers available

2

Company/Institute

University PJ Safarik Kosice

Country

Slovakia

Geofield

Where to apply

E-mail

[email protected]

Contact

City

Košice

Website

https://www.upjs.sk/

Street

Šrobárova 2

Postal Code

O41 80

E-Mail

[email protected]

STATUS: EXPIRED