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, Openness to new scientific directions, interest in gene regulation and epigenetics, Additional advantage: Strong experience in (epi)genome engineering in mammalian cells, molecular cloning, cell
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. To this end, we will employ genome or proteome editing techniques to create worms with misbalanced control of splicing factor levels and determine the resulting phenotypes. Finally, we will analyze
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The spatial organisation of chromatin within the cell nucleus is crucial for the regulation of gene expression, DNA replication, and genome stability. One of the major epigenetic mechanisms influencing 3D
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The International Institute of Molecular Mechanisms and Machines Polish Academy of Sciences | Poland | 2 months ago
of gene regulation and their dysregulation in cancer. Our research seeks to understand how the spatial organization of transcriptional regulators shapes gene expression and cell identity. Project
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molecular and cellular techniques such as gene cloning, PCR, western blotting, transfection and transduction, drug treatment, cell culture, flow cytometry and cell sorting. Experiences in handling mice and
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profiles (R1-R4): R2 Field of science: biology Type of recruitment: NAWA Polish Returns Project: “Transcription factors and their activating mutations: mechanisms of gene expression regulation in health and
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The International Institute of Molecular Mechanisms and Machines Polish Academy of Sciences | Poland | 2 months ago
mechanisms governing transcriptional regulation and their dysregulation in cancer. Our long-term goal is to understand how the spatial organization of transcriptional regulators influences gene expression
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minimum score of 100 points over the past 10 years, providing detailed bibliometric indicators (total Impact Factor, h-index, citations indexed in SCOPUS). Publications: authorship, co-authorship