You will join the project entitled “Identifying unique adaptive responses of red pulp macrophages to iron deficiency” carried out as the SONATA grant (UMO-2020/38/E/NZ4/00511) of the National Science Centre, Poland.
The project aims to significantly advance our understanding of an organism’s adaptation to iron deficiency. Specifically, we identified that low body iron supplies trigger specific but still elusive mechanisms that alter functions of splenic red pulp macrophages, cells that phagocytose aged erythrocytes and thus are responsible for body iron recycling. Our further work aims now to better understand these adaptive responses and determine their physiological role for the whole organism.
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