Postdoctoral Position in hematopoietic stem cell biology (M/W)

-Isolation, sorting, culture of mouse, zebrafish and human HSCs and other haematopoietic populations.
-Transplantation and other tests such as cell cycle assays.
- Fluorescent Activity Cell Sorting (FACS)
-Standard molecular biology techniques
- Next-gen seq and single cell technologies.

The Institute for research on Cancer and Aging, Nice, France invites applications for a Postdoctoral Position in the Laboratory of Eirini Trompouki, which is available for an initial one-year appointment with the possibility of extension.
We are seeking a highly motivated postdoctoral fellow to study how blood-forming stem cells respond to various stress signals like inflammation and aging. We focus on DNA and RNA sensors and their role in hematopoietic stem cell development (Clapes et al., Nature Cell Biology 2021, Lefkopoulos et al., Immunity 2020). We use zebrafish and mice as model organisms but we also employ cell culture to understand mechanistic aspects of in vivo phenotypes (Trompouki et al., Cell 2011, Choudhari et al, Nature Genetics 2020)). Standard techniques that we use include FACS analysis and hematopoietic stem cell transplantation, genome-wide techniques like ChIP-seq, RNA-seq, CLIP-seq, in vivo microscopy together with standard molecular and biochemical techniques. This position is funded by the FRM.

The post-doctoral fellow will be assigned to the Institute for Research on Cancer and Aging Nice (IRCAN UMR7284, U1081) in the team "Molecular Hematology-Blood signals" under the responsibility of Dr Eirini TROMPOUKI
He/She will work in close relation with the scientific leaders.
This position is funded by the FRM.