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plasma and iPSC-derived human disease models. You will investigate disease-related molecular signatures using metabolomics, lipidomics, proteomics and genomics, and combine these data using statistical and
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This doctoral project focuses on establishing isogenic iPSC-derived myelinating organoids as a physiologically relevant human in vitro model of Pelizaeus-Merzbacher-like disease type 1 (PMLD1). You will first
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. These families may face uncertainty about when symptoms will develop and difficult decisions about treatment. Understanding their experiences and support needs is important for developing patient-centred screening
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dvelopment of ARG endpoints in late-stage enteric vaccine trials and identify new strategies to reduce AMR and bacterial infections in at-risk LMIC infants. Where to apply Website https