Postdoctoral position in single cell analysis of cell differentiation in vivo (1.0 FTE)

The Van den Heuvel lab invites applications for a postdoctoral research position in Developmental Biology. The focus of the project will be to reveal the regulatory logic of cellular decision making in the context of animal development. Specifically, we seek to better understand how precursor cells commit to a specialized cellular fate, and how this is coordinated with a permanent arrest of cell division. To address these questions, we will perform detailed quantitative analyses of native cells during their differentiation trajectory in the round worm Caenorhabditis elegans (C. elegans), in combination with sophisticated genetic manipulation. This project will incorporate the latest technologies in transcriptome, epigenome, and proteome analysis, and will be carried out in close collaboration with specialists in computational modeling (Ten Tusscher lab, Utrecht University), single-cell analysis (Korswagen and Van Oudenaarden labs, Hubrecht Institute), and proteomics techniques (Vermeulen lab, Radboud University Nijmegen).

As a postdoctoral Researcher you will become part of the highly interactive Developmental Biology community at Utrecht University. This will include daily interactions with fellow Researchers in the Van den Heuvel, Boxem and Ruijtenberg labs, with graduate students and Postdocs, who work on related topics with one of the consortium partners, and with other Researchers within the Institute of Biodynamics and Biocomplexity (e.g., Akhmanova, Kapitein, Baubec labs) or the broader Utrecht University campus.