PhD student studying pathophysiology of delirium

Updated: 3 months ago
Deadline: 17 Sep 2023

23 Aug 2023
Job Information

University Medical Centre Groningen (UMCG)
Research Field

Medical sciences
Researcher Profile

Recognised Researcher (R2)
First Stage Researcher (R1)

Application Deadline

17 Sep 2023 - 22:00 (UTC)
Type of Contract

Job Status

Not Applicable
Hours Per Week

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme
Is the Job related to staff position within a Research Infrastructure?


Offer Description

The aim of this project is to investigate molecular mechanisms underlying delirium in elderly patients. Delirium is a frequent syndrome characterized by acute confusion. It occurs mainly in the elderly, especially during an infection or after surgery, or in very seriously ill people. In addition to being a very distressing experience for patients and caregivers, delirium is associated with higher mortality and decline in physical and mental functioning. Despite the increasing prevalence with lasting negative consequences, little is known about the pathophysiology of this syndrome. Mechanistically, the interaction between peripheral immune response and brain function is fascinating, and potentially of great significance for understanding aging and other brain diseases.

As a PhD candidate you will conduct experimental and translational scientific research into the pathophysiology of delirium with an immunological focus. You will work at the Department of Medical Biology and Pathology, in the Immunology group of prof. Jon Laman, and closely cooperate with fellow researchers from the University Center for Geriatric Medicine (UCO) and the Alzheimer Center Groningen, and also the European Delirium Association. Such collaboration provides environment where the researchers and medical professionals work closely together on knowledge and hospital care for the elderly, and thus contribute to the healthy aging spearhead of the University Medical Center Groningen. The PhD project will provide the candidate an unique opportunity to obtain knowledge and expertise on important facets of translational research, including the fundamental and clinical research.

Specific Requirements

We are looking for an ambitious candidate having MSc in life science, biotechnology, biology or biochemistry (or related) with a broad interest in various research techniques. You are a real team player, with great communication skills and time management skills. You are able to fluently communicate and write in English. You enjoy working in a fast-evolving research environment, resistant to stress and new scientific and technological challenges.

Als PhD candidate you are responsible for:
- setting up, performing and analyzing experiments, executing and overseeing your own line of research;
- intellectual / scientific contribution to projects designated to your thesis;
- management of the projects;
- giving presentations and writing scientific publications;
- supervising Bachelor and master students.

Additional Information

The position is offered for 36 hours a week for 3,5 years. First, a temporary one-year position will be offered with the option of renewal for another 2,5 years. Your salary will be a minimum of € 2.789,- gross per month in the first year and a maximum of € 3.536,- gross per month (scale PRO) in the final (3,5) year, based on a full-time appointment. In addition, the UMCG will offer you 8% holiday pay, and 8.3% end-of-year bonus. The conditions of employment comply with the Collective Labour Agreement for Medical Centres (CAO-UMC).

Selection process

prof. Jon Laman,
dr. Monika Trzpis,

Additional comments

prof. Jon Laman

dr. Monika Trzpis

Website for additional job details

Work Location(s)
Number of offers available
University Medical Center Groningen (UMCG)
Postal Code
9713 GZ
Hanzeplein 1

Where to apply



Hanzeplein 1
Postal Code

9713 GZ

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