About your role
We are looking for a motivated and enthusiastic PhD candidate for the recently started project DARTBAC: Dutch Antimicrobial Resistance Technology development and Biofilm Assessment Consortium. The performance of novel antimicrobial technologies involving biomaterial applications will be evaluated in ex vivo and in vivo systems, in particular in mouse models of bone or subcutaneous implant infection. You will tailor these models for testing of release systems/coatings with (novel) antimicrobial agents such as synthetic antimicrobial and antibiofilm peptides (SAAPs), photosensitizers, or bioactive glass for their antimicrobial capacity. Subsequently, you will assess the efficacy of novel systems in these models against multi-drug resistant bacteria. Since antimicrobial efficacy is also critically dependent on the host immune response, detailed studies will be performed to analyse cellular immune responses, inflammatory mediators such as cytokines and their regulation. In this way, novel antimicrobial biomaterials can be developed based on the so-called ‘safe-by-design’ principle.
You can find more information on the DARTBAC consortium on the DARTBAC website .
The project
The DARTBAC project aims to develop novel antimicrobial technologies, not based on antibiotics, to target infection prevention and eradication in all tissues and on implant (biomaterial) surfaces. In this way we aim to help prevent the rise of the anti-microbial resistance, which will constitute a major societal impact. DARTBAC is an interdisciplinary consortium consisting of academic partners, technical universities, university medical centres, small and large medical device companies with antimicrobial technologies and knowledge institutes.
Similar Positions
-
Ph D Position On Development Of A Bio Artificial Kidney Device Consisting Of Living Membranes For Improved Kidney Replacement Therapy., University of Twente, Netherlands, about 6 hours ago
Vacancies PhD position on Development of a BioArtificial Kidney device consisting of living membranes for improved kidney replacement therapy. Key takeaways The department of Advanced Organ bioeng...
-
Ph D Position On Development Of A Bio Artificial Kidney Device Consisting Of Living Membranes For Improved Kidney Replacement ..., AcademicTransfer, Netherlands, 16 days ago
PhD position on Development of a BioArtificial Kidney device consisting of living membranes for improved kidney replacement ... PhD position on Development of a BioArtificial Kidney device consist...
-
Ph D On Novel Glaucoma Implant For Real Time Intraocular Pressure Monitoring, Eindhoven University of Technology, Netherlands, about 23 hours ago
Irène Curie Fellowship No Department(s) Mechanical Engineering Reference number V35.7366 Job description Glaucoma drainage devices are vital in treating glaucoma, an eye disease that can cause vis...
-
Ph D Position: Powdery Mildew (Pm) Resistance In Tomato And Pepper, Wageningen University and Research Center, Netherlands, about 8 hours ago
Your job The Laboratory of Plant Breeding at Wageningen university and Research is looking for a highly motivated PhD candidate who is passionate about breeding crops with resistance to diseases ...
-
Ph D Position In Functional Characterization Of Plant Pathogen Effector Proteins , University of Amsterdam, Netherlands, about 4 hours ago
Are you interested in understanding the interaction between plants and pathogens on a molecular level? Do you want to be part of a passionate and curiosity-driven research team? Are you challenged...
-
Ph D Student In Chemokine Immunobiology , Uppsala University, Sweden, 1 day ago
Published: 2024-03-28 PhD student in chemokine immunobiology - HORIZON-MSCA-2022-DN Doctoral Network “B-ACTIVE” These projects, funded by the Marie Skłodowska-Curie Actions (MSCA)-doctoral networ...