10 Feb 2024
Job Information
- Organisation/Company
University Medical Center Utrecht (UMC Utrecht)- Research Field
Medical sciences- Researcher Profile
First Stage Researcher (R1)- Country
Netherlands- Application Deadline
1 Mar 2024 - 22:59 (UTC)- Type of Contract
Temporary- Job Status
Not Applicable- Hours Per Week
36.0- Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme- Is the Job related to staff position within a Research Infrastructure?
No
Offer Description
Brain stimulation methods have shown great promise as a treatment for multiple brain disorders. These methods suffer however from limitations, including poor spatial resolution, which makes it impossible to target specific neuronal circuits, and poorly understood neurophysiological bases, which raises reproducibility concerns. Together with European colleagues, we are developing and testing a groundbreaking method of mechanogenetic stimulation in an interdisciplinary project called SynMech . Our approach is based on the application of functionalized biocompatible magnetic nanoparticles and bioengineered synaptic mechano-sensors that synergistically integrate at specific synaptic connections to repair dysfunctional brain circuits in response to externally applied magnetic fields.
Your role will be to assess the effects of this novel mechanogenetic toolkit on different neurobehavioral, neurophysiological and neuroimaging markers in rodent models of stroke. You will apply the novel experimental treatment, involving intracortical gene and nanoparticle delivery, followed by repetitive transcranial magnetic stimulation (rTMS) in mouse and/or rat models of stroke, together with a biotechnician. You will execute serial in vivo functional MRI, optical imaging, electrophysiological recordings and behavioral tests. You will analyze and correlate multiparametric datasets, which you will frequently discuss with colleagues internally, as well as with international partners within the SynMech consortium.
Requirements
Specific Requirements
- You are a highly motivated scientist with great enthusiasm for experimental and translational brain research.
- You have a master degree in a biomedical field, and you have experience with animal research (preferably with an art. 9 certificate), ideally including imaging/electrophysiology experiments.
- Good computer programming skills are desirable.
- You are eager to learn different techniques and can quickly acquire new competences.
- You are able to work independently as well as in a team.
- You have a good command of both written and spoken English.
Additional Information
Benefits
The maximum salary for this position (36 - 36 hours) is € 3.677,00 gross per month based on full-time employment.
In addition, we offer an annual benefit of 8.3%, holiday allowance, travel expenses and career opportunities. The terms of employment are in accordance with the Cao University Medical Centers (UMC).
Additional comments
Contact our colleague:
Rick Dijkhuizen
0619535515
[email protected]
- Website for additional job details
https://www.academictransfer.com/337644/
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- UMC Utrecht
- Country
- Netherlands
- City
- Utrecht
- Postal Code
- 3584CX
- Street
- Heidelberglaan 100
- Geofield
Where to apply
- Website
https://www.academictransfer.com/en/337644/phd-student-neurotechnology/apply/#a…
Contact
- City
Utrecht- Website
http://www.umcutrecht.nl/- Street
Heidelberglaan 100- Postal Code
3584 CX
STATUS: EXPIRED
Similar Positions
-
Ph D Student Human Milk Extracellular Vesicles For Preterm Brain Development, AcademicTransfer, Netherlands, 23 days ago
PhD student - Human milk extracellular vesicles for preterm brain development PhD student - Human milk extracellular vesicles for preterm brain development Published Deadline Location today 25 Apr...
-
Two Ph D Positions On Understanding Artificial Agents’ Impact On Family Dynamics, AcademicTransfer, Netherlands, 26 days ago
Two PhD Positions on Understanding Artificial Agents’ Impact on Family Dynamics Two PhD Positions on Understanding Artificial Agents’ Impact on Family Dynamics Published Deadline Location today 5 ...
-
Two Ph D Positions ‘Understanding Artificial Agents’ Impact On Family Dynamics’, AcademicTransfer, Netherlands, 26 days ago
Two PhD positions ‘Understanding artificial agents’ impact on family dynamics’ Two PhD positions ‘Understanding artificial agents’ impact on family dynamics’ Geplaatst Deadline Locatie vandaag 5 m...
-
Ph D Student Human Ai Collaboration In Medicine, AcademicTransfer, Netherlands, 23 days ago
PhD student Human-AI collaboration in medicine PhD student Human-AI collaboration in medicine Published Deadline Location today 10 Apr Utrecht We are looking for a PhD student to research ethics i...
-
Ph D Position In Magnetic Metamaterials, European Magnetism Association EMA, Iceland, 12 days ago
Description of the offer : The University of Iceland seeks applicants for a PhD student position within the field of magnetic metamaterials. The position is funded for three years by the Icelandic...
-
Doctoral (Ph D) Student Position In Single Cell Analyses Of Splicing In The Brain, Karolinska Institutet, Sweden, 1 day ago
To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of...