PhD student in Immunology and metabolomics (1.0 FTE)

PhD student in Immunology and metabolomics (1.0 FTE)

Job description We are looking for a PhD student in experimental immunology, with an interest in immunological research on dendritic cell function and metabolomics in health and disease.
In chronic autoimmune diseases such as rheumatoid arthritis (RA) current treatment offer symptomatic relief, but do not cure the disease. Next-generation therapeutic strategies aim at curing RA by restoring the disrupted immune balance. Cell therapy using autologous antigen-loaded tolerogenic dendritic cells (tolDC) is the leading approach. We are currently testing their safety and immunological efficacy in a first-in-man phase I/IIa clinical trial in RA patients. Despite these advances, it remains unclear what exactly confers therapeutic tolDC their tolerogenic functionality. Within this project we want to understand the interplay between metabolic pathways used by tolDC and the relation to functional potency in health and disease.

Qualifications We are looking for an enthusiastic, highly motivated PhD candidate, who is interested in undertaking an interdisciplinary project at the interface of immunology, Metabolism and Metabolomics. You are intrinsically motivated for scientific research and discovery and a team player, who is enthusiastic to bridge research between the Broere and Berkers groups. You are in possession of: 

• a degree (MSc) in biomedical sciences at the interface of cell biology and immunology or equivalent;
• preferably a demonstrated experience in mass spectrometric techniques like metabolomics and/or immunometabolism;
• good technical skills;
• a hands-on attitude, and the ability to work independently;
• self-initiative and you are eager to learn;
• a high level of verbal and written communication skills in English.

Offer

We offer a temporary position (1.0 FTE) for one year in an international working environment. The gross salary - depending on previous qualifications and experience - ranges between €2,395 and €3,061 (scale P according to the Collective Labour Agreement Dutch Universities) per month for a full-time employment. Salaries are supplemented with a holiday bonus of 8% and a year-end bonus of 8.3% per year. In addition, Utrecht University offers excellent secondary conditions, including an attractive retirement scheme, (partly paid) parental leave and flexible employment conditions  (multiple choice model). Here you'll find more information about working at Utrecht University .

About the organization

A better future for everyone. This ambition motivates our scientists in executing their leading research and inspiring teaching. At Utrecht University the various disciplines collaborate intensively towards major societal themes. Our focus is on Dynamics of Youth, Institutions, Life Sciences and Sustainability.
The Faculty of Veterinary Medicine has a unique position in the Netherlands. Not only is this the only institution where veterinarians are trained, researchers are also working together on innovative scientific research. In addition, the faculty provides specialist clinical care in the largest academic veterinary hospital in Europe. Thanks to this position, the Faculty of Veterinary Medicine is a point of contact for all veterinary matters, both nationally and increasingly internationally. The faculty employs approximately 900 veterinarians, scientists and support staff and counts 1.500 students.
A better future for everyone. This ambition motivates our scientists in executing their leading research and inspiring teaching. At Utrecht University disciplines collaborate intensively towards major societal themes. Our focus is on Dynamics of Youth, Institutions for Open Societies, Life Sciences and Sustainability.
The Immunology section is part of the division Infectious Diseases and Immunology within the department Biomolecular Health Sciences, Faculty of Veterinary Medicine , Utrecht University. We offer a supportive and vibrant scientific community that values academic and personal growth.
The Faculty of Veterinary Medicine has a unique position in the Netherlands. It is the only institution where Veterinarians are trained and Researchers are working together in innovative scientific research. In addition, the faculty provides specialist clinical care in the largest academic veterinary hospital in Europe. Thanks to this position, the Faculty of Veterinary Medicine is a point of contact for all veterinary matters, both nationally and increasingly internationally. The faculty employs approximately 900 Veterinarians, Scientists and support staff and counts 1,500 students.

Additional information

For more information, please contact Femke Broere (Professor (section Immunology) [email protected] . 
Please do not send your application letter to this e-mail address.

Apply Everyone deserves to feel at home at our university. We welcome employees with a wide variety of backgrounds and perspectives. 
To apply, please send your curriculum vitae, including a letter of motivation via the button below.
Due to the coronavirus, interviews will be conducted by video calling.

The application deadline is 31/08/2021