PhD position 'the hormonal regulation of mitotic re-activation of differentiated plant cells'

Updated: about 2 months ago
Job Type: Temporary
Deadline: 30 Jan 2021

Are you the biologist with interest in plant development potentially in response to the environment? Do you have affinity with plant hormones? Do you want to contribute to our fundamental research with potential impact on societal challenges and knowledge implementation in crops? Then we are looking for you!

We are looking to recruit a biologists with experience in plant science to join us at the laboratory of Molecular Biology of the Plant Science Group at Wageningen University.

Within the Laboratory of Molecular Biology of the Plant Science Group at Wageningen University, we are looking for a PhD student who is interested in unravelling the hormonal regulation of mitotic re-activation of differentiated plant cells. You will be part of a project funded by an NWO-VIDI grant starting from the first of April.

More about the project
Plants have the remarkable capability of continuously re-activating organogenesis throughout their life. This can be seen in newly formed branches in shoot and root. However, this plasticity is still predetermined, as the site of new branches is already decided at an earlier stage of development when cells are still in an undifferentiated state. Remarkably, some plants show an even greater level of plasticity. Herein new axes of growth originate de novo from differentiated cells that regain mitotic activity. Root nodule formation in legumes is a good example of this de novo organ initiation. Here, fully differentiated cortical cells are mitotically re-activated to form a nodule.

You will use Medicago truncatula. In this model you will investigate developmental processes on a cell-type-specific level by combining highly-sensitive hormone profiling and high-throughput RNA sequencing technologies with cell-type-specific marker lines. Together we will pioneer generating the spatiotemporal hormonal-transcriptional network of de novo organ initiation and will provide novel insights into the processes controlling mitotic re-activation of differentiated (cortical) cells.

More about the Laboratory of Molecular Biology
The Laboratory of Molecular Biology at the Wageningen University is part of the newly formed cluster Plant Developmental Biology (PDB). The research of PDB focuses on plant development potentially in response to the biotic and abiotic environment. PDB brings together a group of highly motivated international scientist with a broad spectrum of expertise that study plant development at various levels ranging from molecular interactions and signalling, cellular dynamics, stem cell development till organ formation and the response of plants to their environment. PDB carries out fundamental research with potential impact on societal challenges and knowledge implementation in crops.


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