1 May 2024
Job Information
- Organisation/Company
Vrije Universiteit Amsterdam (VU)- Research Field
Physics- Researcher Profile
First Stage Researcher (R1)- Country
Netherlands- Application Deadline
9 Jun 2024 - 21:59 (UTC)- Type of Contract
Temporary- Job Status
Not Applicable- Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme- Is the Job related to staff position within a Research Infrastructure?
No
Offer Description
Microbial cell factories are engineered microorganisms that sustainably produce valuable compounds, from biofuels to fine chemicals. Product pathways in these factories are designed to yield desired compounds, with electron flow control being a critical engineering challenge, particularly for optimizing yield. Redox cofactors like NAD+/NADH play a key role in electron transfer, but their involvement in numerous reactions can lead to unintended effects when adjusting product pathways. Our project focuses on minimizing these effects by separating the pathways and metabolic networks, assigning NAD+/NADH for assimilation and a non-canonical redox cofactor for product formation.
In this NWO-XL project 7 PhD students and 2 postdocs from the VU, Wageningen and TU Delft work together to produce such novel cell factories. The role of this PhD position at the VU is to understand the fitness impact of the redox cofactor engineering, and to test robustness of engineered strains. We combine mathematical models (in collaboration with another VU PhD student) with laboratory evolution and physiological characterisation of strains in E. coli and S. cerevisiae.
Requirements
Specific Requirements
A Master in a relevant field, such as microbiology, biotechnology, (bio)physics, or systems biology, or equivalent.
Skills/Qualifications
- Experience in, or affinity with, microbial laboratory evolution and cell physiology
- Experience in, or affinity with, the use of computational methods in biological contexts
- Problem solving
- Independent but willing to ask for help
- Curious
- Communicative in word and text
As a university, we strive for equal opportunities for all, recognising that diversity takes many forms. We believe that diversity in all its complexity is invaluable for the quality of our teaching, research and service. We are always looking for talent with diverse backgrounds and experiences. This also means that we are committed to creating an inclusive community so that we can use diversity as an asset.
We realise that each individual brings a unique set of skills, expertise and mindset. Therefore we are happy to invite anyone who recognises themselves in the profile to apply, even if you do not meet all the requirements.
Additional Information
Benefits
A challenging position in a socially engaged organisation. At VU Amsterdam, you contribute to education, research and service for a better world. And that is valuable. So in return for your efforts, we offer you:
- a salary of € 2.770,00 (PhD) and maximum € 3.539,00 (PhD) gross per month in the fourth year, for a full-time employment
- your employment contract will initially last 1 year and prolonged to 4 years upon a positive evaluation.
We also offer you attractive fringe benefits and arrangements. Some examples:
- A full-time 38-hour working week comes with a holiday leave entitlement of 232 hours per year. If you choose to work 40 hours, you have 96 extra holiday leave hours on an annual basis. For part-timers, this is calculated pro rata.
- 8% holiday allowance and 8.3% end-of-year bonus
- a wide range of sports facilities which staff may use at a modest charge
- discount on (and occasionally exclusive access to) theater performances and courses at the Griffioen Cultural Center
- contribution to commuting expenses
Additional comments
Are you interested in this position and do you believe that your experience will contribute to the further development of our university? In that case, we encourage you to submit your application.
Submitting a diploma is part of the application process.
Applications received by e-mail will not be considered.
Acquisition in response to this advertisement is not appreciated.
- Website for additional job details
https://www.academictransfer.com/341012/
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- Vrije Universiteit Amsterdam
- Country
- Netherlands
- City
- Amsterdam
- Postal Code
- 1081HZ
- Street
- De Boelelaan 1108
Where to apply
- Website
https://www.academictransfer.com/en/341012/phd-position-project-nwo-oc-xl-metab…
Contact
- City
Amsterdam- Website
http://www.vu.nl/- Street
De Boelelaan 1105- Postal Code
1081 HV
STATUS: EXPIRED
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