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PhD position on Metabolic Interactions in the Urinary Tract Microbiome (1.0 FTE) |
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Job description |
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Urinary tract infections (UTIs) are very common in women, with high recurrence rates even after antibiotic treatment. We have indications that a healthy urinary tract microbiome may protect against the development of UTIs, but these preliminary observations require quantification and a solid understanding of the mechanisms. You, as a PhD student, will use the computational tools to analyse and interpret the functioning and dynamics of the urinary tract microbiome. You will apply metagenomics to determine the composition of the urobiome in women with UTIs and healthy controls, annotate the microbial genomes to elucidate their functions, and predict ecological interactions. Based on these data and supported by direct metabolome measurements, you will develop and analyse community models to map metabolite usage, exchange, and trophic dependencies between different microbes in the urobiome. The ultimate goal is to identify potential metabolic intervention points in UTI-associated urobiome. In this project, you will collaborate closely with the University Medical Centre Utrecht (UMCU) and support them in recruiting the cohort of UTI patients. |
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Qualifications |
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We are looking for an enthusiastic new colleague with a strong interest in microbial communities and metagenomics. You have the personal drive to contribute to address a major disease with significant clinical relevance. We would also like you to bring:
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Offer |
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In addition to the employment conditions from the CAO for Dutch Universities, Utrecht University has a number of its own arrangements. These include agreements on professional development , leave arrangements and sports. We also give you the opportunity to expand your terms of employment through the Employment Conditions Selection Model. This is how we encourage you to grow. |
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About the organization |
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A better future for everyone. This ambition motivates our scientists in executing their leading research and inspiring teaching. At Utrecht University , the various disciplines collaborate intensively towards major strategic themes. Our focus is on Dynamics of Youth, Institutions for Open Societies, Life Sciences and Sustainability. |
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Additional information |
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If you have any questions that you’d like us to answer, please contact Dr. Michael Seidl at [email protected] . |
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Apply |
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Everyone deserves to feel at home at our university. We welcome employees with a wide variety of backgrounds and perspectives.
If this specific opportunity isn’t for you, but you know someone else who may be interested, please forward this vacancy to them. |
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The application deadline is |
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26/04/2023 |
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