PhD position on human cardiovascular in vitro models.

Cardiovascular disease is a leading cause of disabling morbidity and mortality. Our mission at the University of Twente is to assess and optimize innovative medical therapies that can elicit favorable effects in the patients and promote heart recovery. For this purpose, this PhD is focused on developing an innovative and unprecedent in vitro cardiovascular twin model of the patient undergoing medical therapy, linking cardiovascular physiology with cell biology. The twin model will combine different in vitro techniques to offer a reliable experimental platform to test medical therapy both on patient hemodynamics and myocardial tissue mechanics. This innovative and unique twin model will provide an alternative low-cost, high throughput and ethically sustainable asset for cardiovascular therapy investigations, with the ultimate goal to foster the improvement of medical therapy and to replace animal experiments.

The work with be conducted in collaboration between two research groups, in a multidisciplinary environment. Join the CRPH and AST groups, and benefit from multidisciplinary team where clinicians, technical physicians, engineers, biochemists and biotechnologists converge.

We offer a young multicultural and collaborative working environment, encouraging interactions among team members, including PhD students, staff members, and principal investigator.

Are you interested in this position? Please send your application via the 'Apply now' button below before 31st of May, and include:

• A cover letter (maximum 2 pages A4), emphasizing your specific interest, qualifications, motivations to apply for this position.
• A Curriculum Vitae, including a list of all courses attended and grades obtained, and, if applicable, a list of publications and references.
• An IELTS-test, Internet TOEFL test (TOEFL-iBT), or a Cambridge CAE-C (CPE). Applicants with a non-Dutch qualification and who have not had secondary and tertiary education in English can only be admitted with an IELTS-test showing a total band score of at least 6.5, internet. TOEFL test (TOEFL-iBT) showing a score of at least 90, or a Cambridge CAE-C (CPE).

The Faculty of Science & Technology (Technische Natuurwetenschappen, TNW) engages some 700 staff members and 2000 students in education and research on the cutting edge of chemical technology, applied physics and biomedical technology. Our fields of application include sustainable energy, process technology and materials science, nanotechnology and technical medicine. As part of a people-first tech university that aims to shape society, individuals and connections, our faculty works together intensively with industrial partners and researchers in the Netherlands and abroad, and conducts extensive research for external commissioning parties and funders. Our research has a high profile both in the Netherlands and internationally and is strengthened by the many young researchers working on innovative projects with as doctoral candidates and post-docs. It has been accommodated in three multidisciplinary UT research institutes: Mesa+ Institute, TechMed Centre and Digital Society Institute.