PhD Position Multiscale modelling of Cardiovascular Tissues

7 Mar 2024
Job Information

Organisation/Company

Delft University of Technology (TU Delft)

Research Field

Technology

Researcher Profile

First Stage Researcher (R1)

Country

Netherlands

Application Deadline

19 Mar 2024 - 22:59 (UTC)

Type of Contract

Temporary

Job Status

Not Applicable

Hours Per Week

40.0

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

Understanding tissue mechanics is crucial to unravel the complexities of diseases, influencing their initiation, progression, and the effectiveness of treatments. Through multiscale computational models, we delve into the mechanical interactions occurring at both cellular and tissue levels. These models play a pivotal role in developing personalized treatment strategies and predicting the onset and progression of cardiovascular diseases. They offer a comprehensive perspective, facilitating the identification of key factors that influence disease dynamics and contributing to the advancement of precision medicine.

In this project, we employ a combination of microscopic imaging, mechanical testing, and multiscale computational modeling to gain insights into the biomechanical behavior of human tissues in both health and disease. Our models, operating at multiple scales – from individual cells to entire tissues and organs – capture the passive and active behaviors of tissues.

This approach enables a thorough exploration of the intricate mechanisms underlying disease processes for the development of more refined and targeted medical interventions.

Such models can help in understanding how mechanical stimuli can influence the progression of the disease. This models can also help in understanding the tissue reponse to mechanical loadings during surgical procedures and in interaction with medical devices. Validation of such models require pre-clinical imaging data that will be aquired in close collaboration with clinicians. These multiscale models are also crucial in the context of Virtual Human Twin (VHT), as promoted by the European commission through EDITH initiative (https://www.edith-csa.eu/ ).

You will work in the CardioVascular Biomechanics Group (https://www.tudelft.nl/me/over/afdelingen/biomechanical-engineering/research/cardiovascular-biomechanics ). The CardioVascular Biomechanics Group is a research group in the BioMechanical Engineering Department at the Mechanical Engineering faculty, formed by five principal investigators that have research interests and expertise in the field of cardiovascular medicine and fluid&tissue biomechanics. The group’s research activities mainly focus on better understanding the structure and biomechanical functioning of the cardiovascular system and its components in health and disease to improve the prevention, diagnosis, and prognosis. This includes vascular biomechanics, thrombus biomechanics, human disease modelling, cardiac biophysics, and haemodynamics.

Requirements
Specific Requirements

The potential candidates are expected to:

• Have a strong interest and/or experience in (multiscale) mechanical modelling of soft tissues
• Hold or about to obtain an MSc degree from a technical program such as (bio)mechanical engineering, material engineering, or similar fields
• Have experience with Finite Element analysis is a plus
• Be creative, a team player and eager to take initiative
• Have good communication skills, and be fluent in both written and spoken English

Please highlight your specific skills for this position explicitly in your motivation letter. Motivation letters that do not address any of these requirements will not be considered.

Doing a PhD at TU Delft requires English proficiency at a certain level to ensure that the candidate is able to communicate and interact well, participate in English-taught Doctoral Education courses, and write scientific articles and a final thesis. For more details please check the Graduate Schools Admission Requirements .

Additional Information
Benefits

Doctoral candidates will be offered a 4-year period of employment in principle, but in the form of 2 employment contracts. An initial 1,5 year contract with an official go/no go progress assessment within 15 months. Followed by an additional contract for the remaining 2,5 years assuming everything goes well and performance requirements are met.

Salary and benefits are in accordance with the Collective Labour Agreement for Dutch Universities, increasing from € 2770 per month in the first year to € 3539 in the fourth year. As a PhD candidate you will be enrolled in the TU Delft Graduate School. The TU Delft Graduate School provides an inspiring research environment with an excellent team of supervisors, academic staff and a mentor. The Doctoral Education Programme is aimed at developing your transferable, discipline-related and research skills.

The TU Delft offers a customisable compensation package, discounts on health insurance, and a monthly work costs contribution. Flexible work schedules can be arranged.

For international applicants, TU Delft has the Coming to Delft Service . This service provides information for new international employees to help you prepare the relocation and to settle in the Netherlands. The Coming to Delft Service offers a Dual Career Programme for partners and they organise events to expand your (social) network.

Selection process

A pre-employment screening can be part of the selection procedure.

Additional comments

Are you interested in this vacancy? Please apply before 20 March 2024 via the application button and upload:

• A cover letter that details your motivation and fit to the job requirements,
• Your CV with a list of (academic and/or industry) references that we can contact
• A list of grades of the qualifying degrees (BSc, MSc)

For more information about this specific position, please contact dr. Behrooz Fereidoonnezhad ([email protected] ) or dr. Frank Gijsen ([email protected] ).

You can apply online. We will not process applications sent by email and/or post.

Please do not contact us for unsolicited services.

Website for additional job details

https://www.academictransfer.com/338708/

Work Location(s)

Number of offers available

1

Company/Institute

Delft University of Technology

Country

Netherlands

City

Delft

Postal Code

2628 CD

Street

Mekelweg 2

Geofield

Where to apply

Website

https://www.academictransfer.com/en/338708/phd-position-multiscale-modelling-of…

Contact

City

Delft

Website

http://www.tudelft.nl/

Street

Mekelweg 2

Postal Code

2628 CD

STATUS: EXPIRED