PhD position in the value assessment of innovations in end-stage organ failure

The four-year PhD position starts on the 2nd of September 2024 (or as soon as possible thereafter). The research project will be embedded in the Health Technology Services (HTSR) department, at the Faculty of Behavioural Management and Social Sciences of the University Twente (UT, The Netherlands).

The PhD candidate will be supervised by dr. Sopany Saing (HTSR), dr. Sebastian Rachuba (Center for Healthcare Operations Improvement & Research), and prof. dr. Erik Koffijberg (HTSR). The candidate will collaborate with dr. Olivier Manintveld (Erasmus UMC, Rotterdam).

Project Description

Competition for limited healthcare resources is a hallmark of any healthcare system. In practice, this translates into a waiting list problem: patients need to wait for a resource to become available, e.g. solid organ transplantation waiting lists and the associated staff and bed/room space needed for the surgery and post-operative care. Compared to timely patient management, delayed interventions commonly result in loss of quality of life, or even death, and additional costs and burden to the healthcare system.

This begs the question, if a technological advancement is introduced into a clinical pathway restricted by resource constraints, how would this affect the waiting time for patients to receive healthcare? In organ transplantation, examples of such advancements include warm perfusion or mechanical circulatory support. Warm perfusion or 'Heart in a Box' allows a donor organ to remain viable for longer outside of the human body. Related to waiting time, there is also a growing concern regarding the shortage of the healthcare workforce. This means that patients are competing for similar healthcare professionals. What does the technological innovation mean for the healthcare workforce? This project will explore how we can measure the true impact of new innovations on available personnel capacity.

The concept of capacity constraints is important in Health Services Research but is typically not considered in Health Technology Assessment (HTA). HTA is a tool relied on by decision makers at both national governments and in some instances, at the hospital level, to determine whether or not to adopt a new technology. Healthcare delivery and the respective healthcare pathways are typically very complex and involve multiple stakeholders and different types of interventions (e.g. diagnostic, pharmaceutical, surgery, rehabilitation…). By incorporating capacity constraints in HTA we can develop a more clinically realistic model. Using simulation modelling techniques allows us to provide better support for decision-making processes at both the National and hospital level.

The overarching objective of the project

The project aims to investigate the health economic, but also broader impact, on healthcare resources, workforce, and the healthcare system, of innovations in the context of end-stage organ failure, using simulation modelling. This broader scope will generate insights beyond traditional HTA outcomes, thereby supporting hospitals and society in making optimal implementation and investment decisions. The model will capture the interaction and competition between the patient, donor organs, healthcare professionals, physical resources and the innovation of interest. In collaboration with cardiologists at Erasmus Medical Centre in Rotterdam we will be exploring the impact of ‘Heart in a Box’ (warm perfusion of donor organ) in end-stage heart failure.

Are you interested to be part of our team? Please submit your application before 17May 2024. Include:

• A cover letter (maximum 2 pages A4) demonstrating your motivation to apply for this position, including how your background, interests and qualifications prepares you to carry out your proposed research plan, and any information about your circumstances relevant to assessing your suitability for the position.
• A Curriculum Vitae, including a list of all courses attended and grades obtained, the title and resume of your bachelor and master thesis. If applicable, a list of publications. Please also include the names, functions, and contact details of two referees whom we may contact.
• An IELTS-test, Internet TOEFL test (TOEFL-iBT), or a Cambridge CAE-C (CPE). Applicants with a non-Dutch qualification and who have not had secondary and tertiary education in English can only be admitted with an IELTS-test showing a total band score of at least 6.5, internet. TOEFL test (TOEFL-iBT) showing a score of at least 90, or a Cambridge CAE-C (CPE).

Additional information can be acquired via email from dr. Saing, [email protected].

At the department of Health Technology and Services Research (HTSR) (https://www.utwente.nl/en/bms/htsr/), multidisciplinary expertise is combined to support decisions on health innovation development, evaluation, optimization, and implementation. Research focuses on quantitative analyses supporting strategies to improve the efficiency and sustainability of healthcare. The HTSR section is part of the Faculty of Behavioural, Management and Social Sciences (BMS, https://www.utwente.nl/nl/bms/) and the Technical Medical Center (TechMed, https://www.utwente.nl/nl/techmed/), a leading innovation hub of the University of Twente.

The Faculty of Behavioral, Management and Social sciences (BMS) aims to play a key role in understanding, jointly developing and evaluating innovations in society. Technological developments are the engine of innovation. As a technical university that puts people first, we tailor them to human needs and behavior and use social engineering to integrate them into society. We also ensure adequate governance at public and private level, and robust, inclusive and fair organizational structures. We do this by developing, sharing and applying high-quality knowledge in Psychology, Business Administration, Public Administration, Communication Sciences, Philosophy, Educational Sciences and Health Sciences. Our research and education in these disciplines revolves around tackling and solving societal challenges. The research programs of BMS are closely linked to the research of the UT institutes Mesa+ Institute for Nanotechnology, TechMed Center and Digital Society Institute.

As an employer, the Faculty of BMS offers work that matters. We equip you to create new possibilities for yourself and for our society. With us, you will become part of a leading technical university with increasing, positive social impact. We offer an open, inclusive and entrepreneurial atmosphere, in which we encourage you to make healthy choices, for example through our flexible, adaptable benefits.