We are looking for a highly motivated and enthusiastic PhD candidate with a strong background in (bio)chemistry, cell biology, (bio)physics or closely related fields to join the Cell Cycle Dynamics group of Dr Julia Kamenz.
In a human body, billions of cells divide every single day. Errors during cell division or uncontrolled cell proliferation can have detrimental consequences including cancer development. Our research focuses on understanding the molecular mechanisms underlying the regulation of cell proliferation and cell division. These studies include (1) the intricate regulation of the kinases and phosphatases involved in the processes of cell division, (2) the impact of post-translational modifications in regulating cell division – in particular phosphorylations – and (3) studying the complex signaling networks surveying and controlling cell cycle progression. Specifically, this PhD project focusses on how multisite phosphorylation of large mitotic complexes defines the temporal dynamics of their functions during mitosis.
To tackle these questions, we combine a variety of cell biological, biochemical and systems biological approaches including Xenopus laevis egg extracts, enzyme biochemistry, fluorescence live cell imaging of human cells and computational modelling. The PhD candidate will have access to state-of-the-art microscopes, mass spectrometry, tissue culture and animal facilities.
The Cell Cycle Dynamics group is embedded in the Molecular Systems Biology unit at the Groningen Biomolecular Sciences and Biotechnology Institute, which provides an inspiring, interdisciplinary and collaborative research environment. The PhD candidate will further receive excellent training through innovative research projects, advanced courses and training opportunities, complemented by workshops on research, transferable skills and teaching. As a PhD candidate, you are committed to conduct independent and original scientific research, to report on this research in international publications and presentations, and to present the results of the research in a PhD dissertation, to be completed within 4 years.
Similar Positions
-
Ph D Bioinformatics Student Sloppiness In M Rna, AcademicTransfer, Netherlands, about 3 hours ago
The research group of Reuven Agami at the division of Oncogenomics at the Netherlands Cancer Institute in Amsterdam has recently uncovered a novel phenomenon in cancer termed “Sloppiness”. They sh...
-
Doctoral (Ph D) Student Position In Single Cell Analyses Of Splicing In The Brain, Karolinska Institutet, Sweden, 2 days ago
To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of...
-
Ph D Student Position In Blood Cancer Research , University of Basel, Switzerland, 21 days ago
The Department of Biomedicine (DBM) is a joint effort between the University of Basel and the University Hospitals Basel. It unites basic and clinical scientists to advance our understanding of he...
-
Multiple Ph D Positions On "Single Cell Proteome Profiling" , ETH Zurich, Switzerland, about 16 hours ago
100%, Zurich, fixed-term The laboratory of Single-Molecule and Single-Cell Biophysics (BMC) is a research group in the Department of Information Technology and Electrical Engineering (D-ITET) at E...
-
Ph D Student In Vascular Cell Biology/Immunology, Leiden University, Netherlands, 6 days ago
Apply now The Faculty of Science and the Institute for Biology Leiden are looking for an: PhD student in vascular cell biology/immunology Key responsibilities The PhD student will work in close co...
-
Ph D Student, Uppsala University, Sweden, about 18 hours ago
Published: 2024-04-23 PhD student at the Department for Medical Cell Biology A four-year fully funded PhD position is now available in Daniel Espes' research group at the Department of Medical Be...