PhD Position in Mass Spectrometry Imaging

Updated: 3 months ago
Deadline: 03 Dec 2023

14 Nov 2023
Job Information

Maastricht University (UM)
Research Field

Medical sciences
Researcher Profile

First Stage Researcher (R1)

Application Deadline

3 Dec 2023 - 22:59 (UTC)
Type of Contract

Job Status

Not Applicable
Hours Per Week

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme
Is the Job related to staff position within a Research Infrastructure?


Offer Description

Mass spectrometry imaging (MSI) is an exciting technique that is gaining popularity in the fields of biomedicine and medical diagnostics for its ability to chemically image tissues without the use of labels [1]. MSI produces images of the locations of biochemical compounds that can help us understand and even better diagnose diseases such as cancer. Along with the rapid growth of computer and imaging systems capable of performing ever more complicated imaging experiments, MSI has recently had several instrumental and methodological advancements that enable it to achieve higher spatial resolution [2], higher molecular information [3], and faster throughput [4] than ever before.

This PhD project aims to develop new MSI instrumentation and corresponding methods to push the boundaries of MSI information content, spatial resolution, and throughput. Multimodal forms of analysis, such as combining MSI with fluorescence microscopy and/or electron microscopy will be an important part of this PhD project. The context for the research is to produce insights, methods, and technologies using multimodal MSI to yield better biomedical information.

Along the way, many of the skills you will develop and use will include electrical engineering, ion and chemical flight modeling, use of advanced imaging technologies and software, analytical and imaging methodologies, programming (both control and data processing software), and chemometrics. Furthermore, you are expected to present your work in scientific journals and at scientific conferences which will utilize skills such as technical writing, public speaking, and study of the current scientific literature base. You will also be able to gain experience teaching and mentoring bachelor and master students.

The PhD position will be supervised by Dr. Ian Anthony and Prof. Ron Heeren. The position is a 4-year long (full-time) paid position at Maastricht University in Maastricht, Netherlands. The anticipated start date is Early Spring 2024, but reasonable accommodations can be made for the right candidate.

  • McDonnell, L. A., Heeren, R. M. A. Mass Spectrom. Rev., 2007, 26 (4), 10.1002/mas.20124
  • Niehaus, M. et al. Nat Methods, 2019, 16 (9), 10.1038/s41592-019-0536-2
  • Bodenmiller, B. Cell Systems 2016, 2, 225-38. 10.1016/j.cels.2016.03.008
  • Körber, A. et al. Anal Chem. 2022, 94 (42) 14652-8. 10.1021/acs.analchem.2c02870

  • Requirements
    Specific Requirements
    • A master’s degree in chemistry, Physics, Materials Science, Chemical Engineering or a related subject
    • Proficiency in English (C1 or higher)
    • Lab experience with chemical or physics instrumentation
    • Capacity to quickly acquire new knowledge and master new skills
    • Interest and ability in hands-on research activities
    • Ability to work independently and as a member of a research team
    • Problem solving skills and creativity
    • A desire and ability to share your research through oral and written communication

    Other skills that would be helpful for the project:

    • Mass spectrometry imaging or data processing
    • Mass spectrometry instrument development, method development, or optimization
    • Instrument control systems and software
    • Ion beams and ion optics
    • Electrical engineering
    • Programming

    Additional Information

    As PhD-candidateat Faculty of Health, Medicine and Life Sciences, you will be employed by the most international university in the Netherlands, located in the beautiful city of Maastricht. In addition, we offer you:

    • Good employment conditions. The position is graded in scale P according to UFO profile Promovendus, with corresponding salary based on experience ranging from €2770,00 and €3539,00 gross per month (based on a full-time employment of 38 hours per week). In addition to the monthly salary, an 8.0% holiday allowance and an 8.3% year-end bonus apply.
    • An employment contract for a period of 12 months with a scope of 1,0 FTE. Upon a positive evaluation, an extension of 3 years will follow.
    • At Maastricht University, the well-being of our employees is of utmost importance, we offer flexible working hours and the possibility to work partly from home if the nature of your position allows it. You will receive a monthly commuting and internet allowance for this. If you work full-time, you will be entitled to 29 vacation days and 4 additional public holidays per year, namely carnival Monday, carnival Tuesday, Good Friday, and Liberation Day. If you choose to accumulate compensation hours, an additional 12 days will be added. Furthermore, you can personalize your employment conditions through a collective labor agreement (CAO) choice model.
    • As Maastricht University, we offer various other excellent secondary employment conditions. These include a good pension scheme with the ABP and the opportunity for UM employees to participate in company fitness and make use of the extensive sports facilities that we also offer to our students.
    • Last but certainly not least, we provide the space and facilities for your personal and professional development. We facilitate this by offering a wide range of training programs and supporting various well-established initiatives such as 'acknowledge and appreciate'.
      The terms of employment at Maastricht University are largely set out in the collective labor agreement of Dutch Universities. In addition, local provisions specific to UM apply. For more information, click here .

    Additional comments

    Are you interested in this exciting position but still have questions? Feel free to contact Dr. Ian Anthony via [email protected] for more information.

    Or are you already convinced and ready to become our new PhD-candidate? Apply now, no later than december 3rd, for this position.

    Interested candidates are invited to submit a cover letter, an up-to-date CV, copies of their tertiary degrees and the contact details of at least two references.

    The vacancy is open for internal and external candidates. In case of equal qualifications, internal candidates will be prioritized.

    Maastricht University is committed to promoting and nurturing a diverse and inclusive community. We believe that diversity in our staff and student population contributes to the quality of research and education at UM, and strive to enable this through inclusive policies and innovative projects led by teams of staff and students. We encourage you to apply for this position.

    Website for additional job details

    Work Location(s)
    Number of offers available
    Maastricht University
    Postal Code
    P. Debyelaan 25

    Where to apply



    Minderbroedersberg 4
    Postal Code

    6211 LK


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