In the research project the PhD candidate is expected to develop and implement pipeline to analyse a variety of clinical and omics (proteomics, transcriptomics, genomics) data sets. This pipeline will be tested on clinical datasets that include multi-omics data such as from Chronic Obstructive Pulmonary Disease (COPD), ovarian cancer, cervical cancer, and head and neck cancer patients. In collaboration with medical experts from these fields the obtained results will be used to shed more light onto important clinical questions: to identify the key molecular mechanisms of these complex diseases, to find biomarkers to improve patient classification, to identify new drug targets, and to support personalised treatment of the patients in the future.
The successful candidate will strongly benefit from working in a highly interdisciplinary research team composed of clinical researchers, analytical chemists, bioinformaticians and statisticians. The different groups, involved in this interdisciplinary project, have an excellent scientific infrastructure and track record in genomics, proteomics, bioinformatics and data integration. University of Groningen has an excellent research infrastructure and the Graduate School of Science of the Faculty of Science and Engineering offer trainings to improve academic and scientific skills.
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