PhD on Real-time Biomolecular Sensing

Updated: 5 days ago
Deadline: 31 May 2023

Are you eager to develop a revolutionary sensing technology with single-molecule resolution in order to enable biomolecular measurements in real time?

Irène Curie Fellowship



Biomedical Engineering

Reference number


Job description
  • We are developing a sensing technology with single-molecule resolution called Biosensing by Particle Motion (BPM). The technology is based on particles attached to a sensing surface that change their mobility due to the binding and release of analyte molecules.
  • Recent publications of our research are: ‘Continuous biomarker monitoring by measuring free particle motion’, Nature Communications (2022); ‘Dynamic response limits of affinity based sensing’, ACS Sensors (2022); ‘Reversible immunosensor for cortisol in blood plasma sampled with microdialysis’, ACS Sensors (2022).
  • Scientific questions relate to biomolecular architectures, signal processing and simulations, microfluidics, measurements in complex biological matrices, calibration methods, etc.
  • Applications include real-time measurements for patient care, lifescience research, and industrial process control.
  • The PhD project will be designed together with you, so tell us about your interests!
  • The project gives opportunities to collaborate with academic and industrial partners, including spin-off company Helia Biomonitoring ( ).
  • You will become a member of the Molecular Biosensing group (MBx, ). Laboratories are shared with the Institute for Complex Molecular Systems ( ). The MBx group initiated and is involved in the international student competition on Sensors for Health ( ).

Job requirements
  • A Master’s degree (or an equivalent university degree) in engineering or in analytical sciences, e.g. chemical engineering, biophysical sciences, biomedical engineering, analytical chemistry.
  • A research-oriented attitude.
  • Ability to work in an interdisciplinary team and interested in collaborating with industrial partners.
  • Motivated to develop your teaching skills and coach students.
  • Fluent in spoken and written English (C1 level).

Conditions of employment

A meaningful job in a dynamic and ambitious university, in an interdisciplinary setting and within an international network. You will work on a beautiful, green campus within walking distance of the central train station. In addition, we offer you:

  • Full-time employment for four years, with an intermediate evaluation (go/no-go) after nine months. You will spend 10% of your employment on teaching tasks.
  • Salary and benefits (such as a pension scheme, paid pregnancy and maternity leave, partially paid parental leave) in accordance with the Collective Labour Agreement for Dutch Universities, scale P (min. € 2.541,- and max. € 3.247,- gross per month).
  • A year-end bonus of 8.3% and annual vacation pay of 8%.
  • High-quality training programs and other support to grow into a self-aware, autonomous scientific researcher. At TU/e we challenge you to take charge of your own learning process .
  • An excellent technical infrastructure, on-campus children's day care and sports facilities.
  • An allowance for commuting, working from home and internet costs.
  • A Staff Immigration Team and a tax compensation scheme (the 30% facility) for international candidates.

Information and application

About us

Eindhoven University of Technology is an internationally top-ranking university in the Netherlands that combines scientific curiosity with a hands-on attitude. Our spirit of collaboration translates into an open culture and a top-five position in collaborating with advanced industries. Fundamental knowledge enables us to design solutions for the highly complex problems of today and tomorrow. 


More information can be obtained from Prof. M.W.J. Prins, Eindhoven University of Technology, m.w.j.prins[at]

Visit our website for more information about the application process and the conditions of employment.

Would like to know more about working at TU/e? Please visit our career page .


We invite you to submit a complete application by using the apply button. Your application should include ALL of the following:

  • Cover letter in which you describe your motivation, your qualifications for the position, and what you would like to learn during your PhD.
  • Curriculum vitae, including a list of scientific projects, scientific reports, and contact information of three references.
  • Lists of courses and grades of your BSc and MSc degrees, as originals and as transcripts.
  • Your final BSc thesis and your final MSc thesis (if available). If these documents are too large, then you can send them by email to: m.w.j.prins[at]

We look forward to receiving your application and will screen it as soon as possible. The vacancy will remain open until the position is filled.

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