The research group ‘Biology of Archaea and Viruses’ is studying infection mechanisms of archaeal viruses. Archaea are ubiquitous microorganisms that form a separate domain of life. Compared with bacteria and eukaryotes, relatively little is known about the cell biology and ecological roles of archaea. A prominent feature of archaea is the extraordinary diversity of their viruses. Archaeal viral particles have many unique shapes not encountered for bacterial and eukaryotic viruses. We focus on the infection strategies of archaeal viruses and study the molecular mechanisms underlying essential steps of the viral infection cycle, such as attachment, entry and release of the host cell. Since these processes take place at the cell surface, we are also actively studying the archaeal cell surface and surface appendages using the halophilic euryarchaeon Haloferax volcanii as a model. Studying the infection mechanisms of archaeal viruses can provide insight into the evolutionary history of viruses and help to understand adaptation to extreme environments. This particular project focusses on novel lysis mechanisms of halophilic viruses.
We offer an excellent opportunity to engage into an exciting PhD project that combines microbiology, genetic, microscopy and biochemical tools in the context of a dynamic and enthusiastic work environment, with state-of-the-art equipment and various chances for national and international scientific collaborations.
We are looking for a PhD candidate for this project. Your responsibilities will include:
• application of several light and electron microscopy techniques to study the infection strategies of selected viruses
• gevelopment of genetic tools for the halophilic virus-host model that is used for the project
• identification and structural characterization of proteins important for the egress of haloarchaeal viruses.
Ph D Student In Molecular And Rna Biology, University of Warsaw, Poland, 5 days ago
In the Structural Biology Group, we study the structure and function of proteins using structural biology methods such as protein crystallography and electron microscopy, bioinformatics analysis a...
Postdoc Position 100% To Establish A Mammalian Intestinal Organoid System , University of Basel, Switzerland, 9 days ago
The Biozentrum of the University of Basel is one of the leading life sciences institutes in the world. It consists of 30 groups and 500 employees that research how molecules and cells create life,...
Post Doctoral Position: Cancer & Metabolism Uc Louvain, Brussels, Belgium, UCLouvain, Belgium, 6 days ago
A 3-year position is available for a postdoctoral scientist to conduct a research project in oncology with a focus on tumor metabolism. Two axes will be considered: (i) the interplay between the t...
Ph D Scholarship: Ubiquitin Signalling Mechanisms In Inflammatory Disease, Technical University of Denmark, Denmark, 24 days ago
A 3-year PhD Scholarship starting 1 May 2022 is available in the Ubiquitin Signalling and Inflammation Laboratory led by Associate Professor Rune Busk Damgaard. Our mission The mission in the Ubiq...
Postdoctoral Position (M/F/D) In Cell Biology, Max Planck Institute of Molecular Cell Biology and Genetics, Germany, about 12 hours ago
We are offering a Postdoctoral Position (m/f/d) in Cell Biology. Job Description Specific targeting and endosomal escape still remain crucial hurdles for successful implementation of macromolecula...
Ph D Position In T Cell Biology, Medical University of Vienna, Austria, about 2 hours ago
A PhD Student position is available to study T cell differentiation at the Institute of Immunology, Medical University of Vienna. Research Area T cells are a major component of the adaptive immune...