The eye is the window to the world around us. Losing vision either early or late in life is a significant burden for patients. Nowadays, molecular therapies for eye conditions are at the forefront of personalized medicine development. However, the eye is a very complex and specialized organ and the lack of relevant and robust models hampers the progress in understanding the disease mechanisms and designing effective treatments. Will you join our group?
In your PhD project you will generate and investigate several retinal cells using from induced pluripotent stem cells from patients suffering from different diseases to find proper measurable readouts. We aim to create a cellular system based on iPSC human cells to generate a retina-on-a-chip to understand disease mechanism(s) and assess therapeutics.
This work will be done in collaboration with the University of Twente and two industrial partners. This project is funded by the Partnership programme Human Measurement models 2.0 for research into the treatment and/or prevention of diseases is funded by the Association of Collaborating Health Foundations (SGF) with a PPP allowance made available by Health~Holland (Top Sector Life Sciences & Health), by ZonMw and NWO Domain AES, and Stichting Proefdiervrij.
Tasks and responsibilities
- Plan and perform scientific in vitro and in vivo experiments in an independent manner.
- Critically analyze data.
- Take a leading role in writing manuscripts.
- Present data at local, national and international scientific meetings.
- Supervise MSc and/or BSc students.
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