PhD Candidate in Cancer Systems Biology: Understanding Metabolic Reprogramming in Triple-negative...
Metabolic reprogramming allows cancer cells to rapidly consume nutrients and produce biomass. Targeting this altered metabolism can be a very effective treatment strategy, but development in this area has been limited. Would you like to start your academic career by tackling these challenges? Then join us as a PhD candidate and help broaden our ability to design effective cancer therapeutics.
You will work on a project funded by the Dutch Cancer Society, focused on identifying metabolic vulnerabilities in triple-negative breast cancer. Your research will include both experimental ('wet-lab') and theoretical ('dry-lab') components. You will have the opportunity to design and conduct a range of experiments in 2D and 3D tissue culture using breast cancer cell lines and patient-derived organoids; develop data-driven models of metabolism and other cellular processes; computationally simulate cancer cell behaviour to predict effective therapeutic targets; and validate your predictions through experimentation. You will gain a strong foundation in the molecular and systems biology of triple-negative breast cancer, state-of-the-art omics technologies, and computational approaches to integrate multi-omics 'big data'.
You will be working in an interactive and multidisciplinary environment in the Molecular Developmental Biology group at RIMLS, under the supervision of Dr Rosemary Yu. As part of your PhD training, you will assist in one or two courses a year and supervise BSc and MSc students within the context of your project.
Your teaching load may be up to 10% of your working time.
Similar Positions
-
Ph D Student Position In Blood Cancer Research , University of Basel, Switzerland, 22 days ago
The Department of Biomedicine (DBM) is a joint effort between the University of Basel and the University Hospitals Basel. It unites basic and clinical scientists to advance our understanding of he...
-
Ph D Student: Machine Learning In Plant Regulatory Genomics, VIB, Belgium, about 4 hours ago
Job description The Vandepoele research lab (Comparative Network Biology - https://www.vandepoelelab.be/ ) invites applications for a fully-funded PhD project for 1 year and extended with another...
-
Ph D Bioinformatics Student Sloppiness In M Rna, AcademicTransfer, Netherlands, about 6 hours ago
The research group of Reuven Agami at the division of Oncogenomics at the Netherlands Cancer Institute in Amsterdam has recently uncovered a novel phenomenon in cancer termed “Sloppiness”. They sh...
-
Ph D Student Human Milk Extracellular Vesicles For Preterm Brain Development, AcademicTransfer, Netherlands, 22 days ago
PhD student - Human milk extracellular vesicles for preterm brain development PhD student - Human milk extracellular vesicles for preterm brain development Published Deadline Location today 25 Apr...
-
Doctoral (Ph D) Student Position In Deep Learning Modeling Of Drug Responses In Cancer, Karolinska Institutet, Sweden, 2 days ago
To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of...
-
Doctoral (Ph D) Student Position Learning Modeling Drug Responses Cancer, SciLifeLab, Sweden, about 4 hours ago
To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of...