PhD Candidate for Epigenetic Regulation of Early Human Embryonic Development

Updated: 24 days ago
Deadline: 09 May 2021

A PhD Candidate in the context of the Marie Curie ITN network EpiSyStem is available to study epigenetic regulation of gene expression in differentiated embryonic stem cells. Various omics approaches next-generation sequencing, interaction proteomics will be used in the project, as well as advanced cell-culture models such as gastruloids.

You will use 'wet-lab' state-of-the-art epigenetic and biochemical techniques and a range of sequencing-based approaches, including single-cell RNA-seq and (singe cell) epigenetic mapping strategies. The large datasets will be analysed using computational approaches, supported by our in-house computational biology unit. The project is embedded within an ambitious and interactive research department, while there are ample opportunities for collaboration within and outside the Netherlands.
As part of your PhD training, you will take part in our medical biology educational programme, for which you will assist in one or two courses per year and will supervise BSc and MSc students within the context of your project.

Marie Curie positions have two compulsory eligibility criteria:
• Applicants must meet the Mobility Rule of the Marie Curie programme: at the time of recruitment by Radboud University, a candidate may not have resided or carried out their main activity (work, studies, etc.) in the Netherlands for more than 12 months in the 3 years immediately prior to the recruitment date.
• Applicants must have had less than four years full-time equivalent research experience (measured from the date when they obtained the degree entitling them to embark on a doctorate) and must not have already obtained a doctoral degree.


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