PhD candidate 'Development of functional breast tomosynthesis: Image reconstruction of functional data for personalized treatment of breast cancer'

17 May 2023
Job Information

Organisation/Company

Radboud University Medical Center (Radboudumc)

Research Field

Medical sciences

Researcher Profile

First Stage Researcher (R1)

Country

Netherlands

Application Deadline

29 May 2023 - 22:00 (UTC)

Type of Contract

Temporary

Job Status

Not Applicable

Hours Per Week

36.0

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

Recent advances in acquisition hardware and computer power have made the acquisition and reconstruction of functional images with x-rays possible. Functional tomosynthesis imaging for acquisition of dynamic perfusion information will provide information on how a breast tumor functions and is reacting to therapy, in addition to their anatomical shape. This new, additional, realm of information obtained about tumor status will aid in personalization of treatment plans and monitoring of the response to treatment. However, the implementation of functional tomosynthesis requires development and optimization of image acquisition and processing methods to solve the image reconstruction inverse problem for a dynamic object at lower radiation doses with high noise levels, while maintaining high image quality characteristics.

The AXTI lab is engaged in the development of cutting-edge digital breast tomosynthesis systems for functional imaging of the breast. This project involves the development, optimization, characterization, and patient testing of the first such system in the world.

In this project you will develop novel tomosynthesis image reconstruction algorithms, including motion compensation and regularization, validate these methods using digital and physical functional phantoms, and participate in the development of radiomics analysis of the generated 3D and 4D image volumes. There will be close collaboration with other team members focusing on system modelling, acquisition optimization, and phantom design, and industry partners to facilitate the translation of these methods into clinical evaluation and use. Tasks will also include presenting at international scientific conferences and writing papers on newly developed methods and the study results.

Requirements
Specific Requirements

We are looking for a creative and enthusiastic researcher with a MSc degree in physics, mathematics, computer science, engineering, medical physics, or similar. You have experience or interest in inverse problems and their applications in radiology and/or image processing, and affinity with biomedical research. You also have experience in programming in python, C/C++, Matlab, or similar. Lastly, you have excellent communication skills in English, both written and spoken.

Additional Information
Benefits

The salary depends on education. Scale 10 will be offered to MSc medical graduates; those holding degrees in other disciplines will be offered scale 10A.

Working at Radboud university medical center means that you are ahead of the curve and working together on the healthcare of the future. And there is more. Our secondary terms of employment are impressive. These are fully tailored to you thanks to our Employment Conditions Selection Model. At Radboud university medical center, you will be given trust, and you will take the responsibility to handle everything together. We provide annual courses, both professional and personal.

• A gross monthly salary between € 2.789 and € 3.536 (scale 10A) or between € 3.230 and € 5.088 (scale 10) based on full-time employment.
• From 1 November 2023 the wages will increase by 4%.
• An annual vacation allowance of 8% and an end-of-year bonus of 8.3%.
• If you work irregular hours, you will receive an allowance.
• As a full-time employee (36 hours per week), you are entitled to approximately 168 vacation hours (over 23 days) per year.
• Radboud university medical center pays 70% of the pension premium. You pay the rest of the premium with your gross salary.
• You get a discount on health insurance as well: you can take advantage of two group health insurance plans. UMC Zorgverzekering and CZ collectief.

In addition to our terms of employment , we also offer employees various other attractive facilities, such as childcare and sports facilities. Want to learn more? Take a look at the Cao UMC .

Selection process

The following should be included in your application: CV, letters of recommendation, list of completed courses and grades, a letter of motivation, and reprints or, preferably, links to your thesis or any scientific publications or reports in English that you have written.

Any questions? Please contact dr. Ioannis Sechopoulos , associate professor. Use the Apply button to submit your application.

Additional comments

The following should be included in your application: CV, letters of recommendation, list of completed courses and grades, a letter of motivation, and reprints or, preferably, links to your thesis or any scientific publications or reports in English that you have written.

Any questions? Please contact dr. Ioannis Sechopoulos , associate professor. Use the Apply button to submit your application.

Website for additional job details

https://www.academictransfer.com/327878/

Work Location(s)

Number of offers available

1

Company/Institute

Radboudumc

Country

Netherlands

City

Nijmegen

Postal Code

6525 GA

Street

Geert Grooteplein-Zuid 10

Where to apply

Website

https://www.academictransfer.com/327878/phd-candidate-development-of-functional…

Contact

City

Nijmegen

Website

http://www.radboudumc.nl/

Street

Geert Grooteplein-Zuid 10

Postal Code

6525 GA

STATUS: EXPIRED