PhD position in METABOLISM IN CANCER AND ANGIOGENESIS

Updated: about 1 month ago
Job Type: FullTime
Deadline: 23 Apr 2021

The laboratory on Prof. Massimo Santoro (www.massimosantorolab.com ) is seeking a PhD student to study the role of metabolism in cancer and angiogenesis (Santoro, Cell Metabolism, 2020: Arslanbaeva and Santoro, Redox Biology, 2020; Donadon and Santoro, Development, 2021). Our team has recently identified a set of novel metabolic enzymes that is crucial for regulation of cancer and vascular development (Mugoni et al., Cell 2013, Chen et al., Cell Reports, 2017; Facchinello et al., 2021 in revision; Tosi et al., 2021, in preparation). Using mouse genetic approaches as well as advanced molecular and microscopic techniques we want to elucidate how lipid signaling and metabolism regulate melanoma survival and progression. Our laboratory has acquired strong experience in biochemistry, genetic, molecular and cellular biology of endothelial and cancer cells and animal models. Mouse animal facility, single cell RNA-seq, STED, multiphoton, light sheet microscopy equipment, and metabolic/proteomic core facilities are available in the laboratory and department. We believe that such studies offer unique opportunities for designing new therapeutic strategies against metastasis and cancer spreading.

Applicants for PhD position should hold a Master degree in biology, biomedical sciences, bioengineering, medicine or any related discipline. Motivated students of all nationalities with a strong commitment to basic and/or clinical research are invited to apply. Any experience in molecular biology, cellular and developmental biology, biochemistry, cell culture, metabolism, is an advantage. The candidate should have well-developed social skills, been able to work in a team, have good communication skills in spoken and written English.

Contact

Please send your CV, letter of motivation, and the contact information of at least two references to Prof. Santoro at massimo.santoro@unipd.it .


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