PhD Studentship in Clinical Microbiology - Invasive Fungal Infections

Updated: 30 days ago
Location: Ireland,
Job Type: Temporary
Deadline: 18 Oct 2020

Post Specification

Post Title:

PhD Studentship

Post Status:

Fixed-term (Full-time)

Research Group / Department / School:

Discipline of Clinical Microbiology, School of Medicine, Trinity College Dublin, the University of Dublin

Location:

Trinity Translational Medicine Institute, and Sir Patrick Dun Labs, Central Pathology Laboratory, St. James’s Hospital, Dublin 8, Ireland

Reports to:

Associate Professor Johannes Wagener (wagenerj@tcd.ie )

Terms & Conditions:

Stipend (€16,000 per year) and academic fee coverage

Closing Date:

12 Noon (GMT), 18st October 2020

NOTE: Applicants must have been resident in an EU member state for 3 out of the last 5 years to be eligible for EU fees

Post Summary

Fungi cause a wide range of diseases in humans and animals. With an increasing number of immunocompromised patients, the frequency of life-threatening invasive fungal infections (IFIs) caused by yeasts of the genus Candida and moulds of the genus Aspergillus is on the rise. Main reasons for the often fatal outcome of IFIs are late diagnosis, inefficient treatment options and antifungal resistance.

Our research focuses on the diagnosis, treatment and infection biology of human fungal infections. The successful candidate will conduct basic and applied research in the area of IFIs using microbiology, molecular biology, microscopy and immunology techniques. The student will primarily work in a research group in medical mycology at Trinity Translational Medicine Institute, and Sir Patrick Dun Labs at St. James’s Hospital in Dublin and collaborate with an experienced international team of basic scientists and medical professionals.

Standard Duties and Responsibilities of the Post

The successful candidate will undertake postgraduate research in the area of IFIs. He/she will learn and exert techniques such as genetically manipulate fungal cells, isolate immune cells, perform antimicrobial susceptibility testing, SDS-PAGE, Western blot, PCR, fluorescence microscopy, and bioinformatics. The PhD student will regularly participate in group meetings and institutional seminars, which includes giving progress reports about ongoing research. The PhD student is expected to present project results on scientific conferences and publish research outputs in international peer-reviewed scientific journals. The successful candidate will work effectively and closely with other members of a multidisciplinary and international team of basic scientists and physician scientists.

Funding Information

This post is funded by the Discipline of Clinical Microbiology, School of Medicine, Trinity College Dublin, the University of Dublin

Person Specification

Qualifications

The ideal applicant has a first or upper second-class bachelor’s or master’s degree (or equivalent) in Molecular Medicine, Immunology, Biochemistry, Microbiology or a related discipline.

Knowledge & Experience

  • You have a strong interest in cell and infection biology
  • You have in-depth knowledge of molecular biology
  • You have expertise in immunology and understanding of genetics
  • You have experience in bioinformatics
  • You have experience with cell culture or microbiological techniques
  • Experience in microscopy and immune cell isolation is advantageous

Skills & Competencies

Strong written and oral communication skills.

Application Procedure

Applications should include a letter of interest, curriculum vitae, copies of certificates, and names of up to three academic references.

Informal enquiries about this post can be made to Johannes Wagener (wagenerj@tcd.ie ).

Applications should be submitted as a single PDF file by e-mail (subject line: PHD2020_WEX) to:

Dr. Johannes Wagener

Associate Professor / Consultant, Clinical Microbiology

wagenerj@tcd.ie

Further Information for Applicants

URL Link to Area

www.tcd.ie

URL Link to Human Resources

https://www.tcd.ie/hr/

URL Link to School

https://www.tcd.ie/medicine/

URL Link to Discipline

https://www.tcd.ie/medicine/clinical_microbiology/


Trinity College Dublin, the University of Dublin

Trinity is Ireland’s leading university and is ranked 108th in the world (QS World University Rankings 2020). Founded in 1592, the University is steeped in history with a reputation for excellence in education, research and innovation.

Located on an iconic campus in the heart of Dublin’s city centre, Trinity has 18,000 undergraduate and postgraduate students across our three faculties – Arts, Humanities, and Social Sciences; Engineering, Mathematics and Science; and Health Sciences.

Trinity is ranked as the 17th most international university in the world (Times Higher Education Rankings 2020) and has students and staff from over 120 countries.

The pursuit of excellence through research and scholarship is at the heart of a Trinity education, and our researchers have an outstanding publication record and strong record of grant success. Trinity has developed 19 broad-based multidisciplinary research themes that cut across disciplines and facilitate world-leading research and collaboration within the University and with colleagues around the world. Trinity is also home to 5 leading flagship research institutes:

  • Trinity Biomedical Sciences Institute (TBSI)
  • Trinity College Institute of Neuroscience (TCIN)
  • Trinity Translational Medical Institute (TTMI)
  • Trinity Long Room Hub Arts and Humanities Research Institute (TLRH)
  • Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN)

Trinity is the top-ranked European university for producing entrepreneurs for the past five successive years and Europe’s only representative in the world’s top-50 universities

(Pitchbook Universities Report).

Trinity is home to the famous Old Library and to the historic Book of Kells as well as other internationally significant holdings in manuscripts, maps and early printed material. The Trinity Library is a legal deposit library, granting the University the right to claim a copy of every book published in Ireland and the UK. At present, the Library’s holdings span approximately 6.5 million printed items, 400,000 e-books and 150,000 e-journals.

With over 120,000 alumni, Trinity’s tradition of independent intellectual inquiry has produced some of the world’s finest, most original minds including the writers Oscar Wilde and Samuel Beckett (Nobel laureates), the mathematician William Rowan Hamilton and the physicist Ernest Walton (Nobel laureate), the political thinker Edmund Burke, and the former President of Ireland Mary Robinson. This tradition finds expression today in a campus culture of scholarship, innovation, creativity, entrepreneurship and dedication to societal reform.

Rankings

Trinity is the top ranked university in Ireland and ranked 108th in the world (QS World University Rankings 2020). Trinity ranks in the top 50 in the world on 6 subjects and in the top 100 in 20 subjects (QS World University Rankings by Subject 2019). Full details are available at: www.tcd.ie/research/about/rankings .

The Selection Process in Trinity

The Selection Committee (Interview Panel) may include members of the Academic and Administrative community together with External Assessor(s) who are expert in the area. Applications will be acknowledged by email. If you do not receive confirmation of receipt within 1 day of submitting your application online, please contact the named Recruitment Partner on the job specification immediately and prior to the closing date/time.

Given the degree of co-ordination and planning to have a Selection Committee available on the specified date, the University regrets that it may not be in a position to offer alternate selection dates. Where candidates are unavailable, reserves may be drawn from a shortlist. Outcomes of interviews are notified in writing to candidates and are issued no later than 5 working days following the selection day.

In some instances the Selection Committee may avail of telephone or video conferencing. The University’s selection methods may consist of any or all of the following: Interviews, Presentations, Psychometric Testing, References and Situational Exercises.

It is the policy of the University to conduct pre-employment medical screening/full pre-employment medicals. Information supplied by candidates in their application (Cover Letter and CV) will be used to shortlist for interview.

Applications from non-EEA citizens are welcomed. However, eligibility is determined by the Department of Business, Enterprise and Innovation and further information on the Highly Skills Eligible Occupations List is set out in Schedule 3 of the Regulations https://dbei.gov.ie/en/What-We-Do/Workplace-and-Skills/Employment-Permits/Employment-Permit-Eligibility/Highly-Skilled-Eligible-Occupations-List/ and the Ineligible Categories of Employment are set out in Schedule 4 of the Regulations https://dbei.gov.ie/en/What-We-Do/Workplace-and-Skills/Employment-Permits/Employment-Permit-Eligibility/Ineligible-Categories-of-Employment/ . Non-EEA candidates should note that the onus is on them to secure a visa to travel to Ireland prior to interview. Non-EEA candidates should also be aware that even if successful at interview, an appointment to the post is contingent on the securing of an employment permit.


Equal Opportunities Policy

Trinity is an equal opportunities employer and is committed to employment policies, procedures and practices which do not discriminate on grounds such as gender, civil status, family status, age, disability, race, religious belief, sexual orientation or membership of the travelling community. On that basis we encourage and welcome talented people from all backgrounds to join our staff community. Trinity’s Diversity Statement can be viewed in full at https://www.tcd.ie/diversity-inclusion/diversity-statement .


Application Procedure


Application Procedure

Applicants should submit a letter of interest, curriculum vitae, copies of certificates, and names of up to three academic references as a single PDF file by e-mail (subject line: PHD2020_WEX) to:

wagenerj@tcd.ie


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