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candidate is expected to develop new cell and animal models, as well as biomarkers for neurodegenerative diseases. Patient plasma samples will be collected and the circulating extracellular vesicles will be
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"Elucidating the underlying mechanisms of action of a drug candidate both in inflammation and cancer." -Required research experience: cell culture, cytotoxicity techniques, DNA isolation, polymerase chain
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cutting-edge techniques, including immunoassays for organic contaminants, RNA quantification for harmful microalgae and bacteria, and genetically modified whole cell biosensors for heavy metal
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to hyperpolarize the cell and ensure removal of NaV1.1 inactivation for fast spiking. In DS this mechanism becomes compromised causing cell depolarization and inactivation of voltage-gated channels at large present
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, Australia (Prof. L. Palmer), and the University of Dublin, Ireland (Prof. T. Ryan). The successful applicant will use computational methods (e.g., similar to Kastellakis et al., Cell Reports, 2016 or other