Area of research:
Scientific / postdoctoral posts
Area of research:
Single-cell RNA sequencing (scRNA-seq) technologies are changing the way biology is done, and have been widely applied to eukaryotic systems. Recent developments, including work at the HIRI (Imdahl et al. “Single-cell RNA-sequencing reports growth-condition-specific global transcriptomes of individual bacteria”, Nature Microbiology, 2020), have made scRNA-seq in bacteria possible. These methods open up new possibilities for investigating the effects of expression heterogeneity during infection and on antibiotic tolerance and resistance. The Barquist lab is now recruiting a postdoctoral researcher to develop analyses tailored to scRNA-seq of bacterial pathogens. All work will be done in close collaboration with experimentalists from the Vogel and Saliba groups at HIRI. The successful candidate will work in a team with deep experience in the analysis and interpretation of functional genomics data, with access to world-class computational resources located at the HZI, JMU, and within the Helmholtz Association. Opportunities will be available for the candidate to develop their own research projects in the bacterial scRNA-seq space with the support of experimental groups at the HIRI, depending on candidate background and interest.
- PhD or equivalent in Computational Biology, Bioinformatics, Microbiology or a related field in the computational or biological sciences
- Proven experience in the analysis of sequencing data using Python and R/Bioconductor packages
- Experience working in a Linux-based high-performance computing environment
- Strong written and spoken English language communication skills
Desired (non-essential) background:
- Previous experience with single-cell RNA-seq
- Experience with scientific workflow development (e.g. Nextflow, Snakemake)
- Basic knowledge of microbiology or infection biology, or a strong desire to learn
Salary:E13 TVöD Bund
This research center is part of the Helmholtz Association of German Research Centers. With more than 42,000 employees and an annual budget of over € 5 billion, the Helmholtz Association is Germany's largest scientific organisation.
Postdoctoral Position: Dissecting The Cellular Landscape Of Equine Asthma Using Single Cell Genomics Application Deadline: April 15, 2021view, SciLifeLab, Sweden, about 18 hours ago
Uppsala University is a comprehensive research-intensive university with a strong international standing. Our ultimate goal is to conduct education and research of the highest quality and relevanc...
Postdoctoral Position: Dissecting The Cellular Landscape Of Equine Asthma Using Single Cell Genomics , Uppsala University, Sweden, about 8 hours ago
Published: 2021-03-25 Uppsala University is a comprehensive research-intensive university with a strong international standing. Our ultimate goal is to conduct education and research of the highe...
Ph D Candidate For Epigenetic Regulation Of Early Human Embryonic Development, Radboud University, Netherlands, about 23 hours ago
A PhD Candidate in the context of the Marie Curie ITN network EpiSyStem is available to study epigenetic regulation of gene expression in differentiated embryonic stem cells. Various omics approac...
Doctoral Position (F/M/D) In Computational Biology And Machine Learning (E13/65 %) , Technical University of Munich, Germany, about 20 hours ago
24.03.2021, Wissenschaftliches Personal The Institute for Medical Microbiology, Immunology and Hygiene (MIH) at the Technical University of Munich is looking for a doctoral candidate (f/m/d) to jo...
Postdoctoral Studies On The Biology Of Tumor Invasion (Scholarship), Karolinska Institute, Sweden, about 1 hour ago
The Department of Biosciences and Nutrition performs research and education in several areas of medical science including aging, Alzheimer, biomaterial, molecular endocrinology, cancer biology, fu...
Doctoral Researcher (F/M/D), Leibniz, Germany, 1 day ago
The Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute (Leibniz-HKI, www.leibniz-hki.de ) investigates the pathobiology of human-pathogenic fungi and ident...