PlasmACT: PhD position in membrane lipid modifications and dynamics of plasma-mediated biological activity and toxicity

Updated: 3 months ago
Location: Greifswald, MECKLENBURG VORPOMMERN
Job Type: FullTime
Deadline: 11 Mar 2024

31 Jan 2024
Job Information
Organisation/Company

Leibniz Institute for Plasma Science and Technology
Department

ZIK plasmatis
Research Field

Chemistry » Biochemistry
Researcher Profile

First Stage Researcher (R1)
Country

Germany
Application Deadline

11 Mar 2024 - 23:59 (Europe/Berlin)
Type of Contract

Temporary
Job Status

Full-time
Hours Per Week

40
Offer Starting Date

3 Jun 2024
Is the job funded through the EU Research Framework Programme?

HE / MSCA
Marie Curie Grant Agreement Number

101118430
Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

Short overview of PlasmACT:

The PlasmACT network brings together 5 beneficiaries and 10 associated partners, located in 5 different countries (Germany, France, Netherlands, Belgium, and Luxembourg). Eight Doctoral candidates will enjoy a multi-disciplinary and international environment with plenty of training opportunities and exchange with all institutions involved in the network.

Scientific Background:

The quality of human (and veterinary) health care systems substantially depends on key innovations. Often, these were driven by the field of physics, followed by interdisciplinary and inter-sectorial actions in engineering, chemistry, biology, and medicine. By using beyond state-of-the-art plasma multijet technology, the primary technical objective of PlasmACT is to support skin cancer prevention by medical gas plasma therapy of Actinic Keratosis.

The project assesses the biochemistry aspects of gas plasma treatment in actinic keratosis. This includes the analysis of protein expression and post-translational modifications, including oxidative modifications, of in vitro cultured cells obtained by this DC as well as specimens from animal experiments and patients obtained by other PlasmACT DCs. The research aspects potentially extend to immunopeptidomics analysis. Technically, the main method to be employed is ultra-high-performance liquid chromatography coupled with high-resolution mass spectrometry, and the project tasks the entire mass spectrometry workflow from sample generation, sample preparation, sample acquisition, and sample analysis. In addition, two secondments to an academic and industrial partner institution are already planned to broaden the network and differentiate the student's skills and knowledge. Furthermore, the project provides ample opportunities for professional exchange and networking with other academic and industrial partners.

The Leibniz Institute for Plasma Science and Technology (INP) is the largest non-University Research Institute on Cold Physical Plasma Technology in Europe. About 200 people work at INP across all major disciplines, from physics and engineering, over chemistry and material science, to biochemistry and biomedicine. A spin-off from INP Greifswald, neoplas med GmbH, was the first to launch an accredited atmospheric pressure argon plasma jet into the European market for chronic wound treatment.

 


Requirements
Research Field
Biological sciences
Education Level
Master Degree or equivalent

Research Field
Chemistry » Biochemistry
Education Level
Master Degree or equivalent

Research Field
Engineering
Education Level
Master Degree or equivalent

Skills/Qualifications
  • Mass spectrometry analysis, the main type of experiment in this project, requires a strong affinity to computer processes, software operation, and large data handling
  • Programming skills are an asset but are not required

Languages
ENGLISH
Level
Excellent

Additional Information
Benefits

Doctoral candidates are offered a competitive remuneration based on the MSCA allowances in line with the MSCA WP 2021-2022 .


Eligibility criteria
  • Applicants must be doctoral candidates, i.e not already in possession of a doctoral degree at the date of recruitment.
  • Mobility rule: researchers must not have carried out their main activity (e.g. work, studies) at the host country for more than 12 months in the 3 years immediately before their recruitment date.
  • DC applicants must fulfil the local recruiting requirements.
  • The date of Master Degree obtainment must not be older than 3 years from the date when the position starts.

Selection process

Candidates should apply with PlasmACT DN application form available on the project website (www.PlasmACT.eu ) and transcripts as a single file.

Submitted applications will be evaluated according to the European Code of Conduct for Recruitment (https://euraxess.ec.europa.eu/jobs/charter/code ). Your performance and personality count, regardless of your age, origin, gender, sexual identity, disability or ideology. The INP wants equal participation of men and women, especially in science. Qualified female applicants are explicitly encouraged to apply. Disabled applicants will be given preferential consideration if they are equally qualified.

Shortlisted candidates will be invited for interviews expected in April 2024. Shortlisted candidates will be notified about the selection process outcome. Unfortunately, we cannot refund any expenses associated with the application or job interview due to budgetary regulations.

Applicants interested in the position will also have to apply to the PhD Program. Employment will be conditioned by acceptance to the program.


Website for additional job details

https://plasmact.eu/vacancies/

Work Location(s)
Number of offers available
1
Company/Institute
Leibniz Institute for Plasma Science and Technology (INP)
Country
Germany
City
Greifswald
Street
Felix-Hausdorff-Str. 2
Geofield


Where to apply
Website

https://plasmact.eu/vacancies/

Contact
City

Greifswald
Website

http://www.inp-greifswald.de
Street

Felix-Hausdorff-Straße 2
Postal Code

17489
E-Mail

[email protected]

STATUS: EXPIRED