We are hiring a
PhD student or Postdoc (m/f/d)
in Cell Biology.
The group of Marino Zerial is looking for a highly-motivated candidate with strong background in cell biology to work on the delivery of oligonucleotide therapeutics.
Specific targeting and endosomal escape still remain crucial hurdles for successful implementation of macromolecular therapeutics. The know-how in endocytosis positions the group at the leading edge of the studies of macromolecule-based drug delivery systems.
This project aims to investigate the intracellular trafficking of non-viral gene delivery technologies. The uptake, trafficking and endosomal escape of nucleic acids will be analysed in cell lines and primary cells in vitro, and in mouse models in vivo, using quantitative light and electron microscopy approaches. This project will provide proof of concept for new platforms enabling cellular delivery of oligonucleotides in vitro and in vivo and demonstrate the therapeutic potential of the approach. The project will be carried out in collaboration with a major pharmaceutical company.
The successful candidate should hold a degree in life sciences and have documented experience in cell biology and fluorescence microscopy imaging. Experience in in vivo studies with mice will be an advantage. The candidate should be able to interact with members of an interdisciplinary team of cell biologists, physicists, chemists and computer scientists, work in a competitive international environment and possess excellent communication and data presentation skills (English is the working language at the MPI-CBG).
The full-time position is available immediately for an initial period of 2 years with the possibility of extension. Salary and social benefits will be in accordance with the regulations of the German TVöD Bund (salary agreement for public service employees).
For further information contact Dr. Lisa Johnsen by email johnsen mpi-cbg.de or phone +49 (0) 351 210 2136.
Candidates interested in performing their PhD work on the above project should apply directly to the International Max Planck Research School for Cell, Developmental and Systems Biology (https://www.imprs-celldevosys.de/ ), following the guidelines of the program.
Postdoctoral candidates should submit their complete application including the names of three referees by 16.08.2021 via our online application system stating Code 2021-PostDoc-Cellbiology-1040 at https://recruitingapp-2443.umantis.com/Vacancies/462/Application/CheckLogin/2?lang=eng
The Max Planck Society strives for gender and diversity equality. We welcome applications from all backgrounds.
Max Planck Institute of Molecular Cell Biology
Pfotenhauerstr. 108, 01307 Dresden, Germany
Ph D Position On Hydrogels For Cell Encapsulation And Soft Tissue Repair, University of Twente (UT), Netherlands, about 14 hours ago
A fully financed 4yr PhD position at the interface of polymer chemistry, biomaterials synthesis, and biomedical sciences; is available at the Faculty of Science and Technology, University of Twent...
Ph D Candidate For Unravelling Cellular Glycosylation Mechanisms, Radboud University, Netherlands, about 13 hours ago
The process of protein glycosylation regulates many biochemical properties and molecular functions, but these versatile biomolecules are currently not well understood. As a PhD Candidate, you will...
Ph D Fellowship On Nuclear Envelope Dynamics In Cancer Cells (Ref 210525), University of Oslo, Norway, 6 days ago
The Campsteijn lab seeks a highly motivated PhD student candidate to study the molecular mechanisms ensuring nuclear integrity and their role in cell fitness and fate. Major breakthroughs over the...
Ph D Student Scholarship, Institute of Animal Reproduction and Food Research of Polish Academy of Sciences, Poland, 1 day ago
Person specification (desired skills): - MSc in molecular biology, cell signalling or related biological discipline - Basic knowledge on cell signalling studies (desired) - Previous experience in ...
Ph D Fellowship In Mechanobiology , University of Basel, Switzerland, about 5 hours ago
The Biozentrum of the University of Basel is one of the leading life sciences institutes in the world. It consists of 30 groups and 500 employees that research how molecules and cells create life,...
Ph D Candidate Rheumatology Autoreactive B Cells, Leiden University Medical Center (LUMC), Netherlands, 20 days ago
Autoreactive B cells play a central role in rheumatoid arthritis (RA), as demonstrated by the remarkable response of patients to B cell targeted therapies. Our team recently identified that RA is ...