PhD student (m/f/d) to work on adoptive T cell therapy of cancer

Updated: 3 months ago
Location: Germany,
Job Type: PartTime
Deadline: 27 Dec 2020

*The LMU University Hospital Munich is one of the largest and most efficient university hospitals in Germany and Europe. 48 specialized clinics, departments and institutes provide excellent research and teaching and enable interprofessional and interdisciplinary patient care at the highest level. Our employees come from more than 100 countries.*
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The Division for Clinical Pharmacology on the Campus Innenstadt invites applications for the immunopharmacology group, in part time, for a

h2. PhD student (m/f/d) to work on adoptive T cell therapy of cancer

h3. Abteilung für Klinische Pharmakologie
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*Scope of duties*

Chimeric antigen receptor (CAR) T cell therapy has become the gold standard for several hematological malignancies. The scope of indications of this therapeutic modality is rapidly expanding with promising studies being launched also in solid tumors. Simultaneously, research in the CAR T cell field also has a strong focus on toxicity mechanisms, treatment and prevention thereof. CAR T cell therapy is a living therapy infused in patients which will remain active and in circulation for decades. Conventional pharmacokinetic and pharmacodynamic studies are not appropriate for this therapeutic modality and there is an urge for pre-clinical models that can be used to extensively test these therapies. This PhD position will focus on the study of CAR T cell therapies.

The working group offers an exciting scientific environment with international colleagues. This PhD position will be integrated in existing PhD programs in the Division for Clinical Pharmacology (Director: Prof. S. Endres; www.klinische-pharmakologie.de ). The Division for Clinical Pharmacology works on an internationally competitive level on topics concerning innate immunity and tumor immunology.
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*Our requirements*

We expect applications from graduate students of medicine, biology, immunology or pharmacy with an excellent academic background. Applications can come from Germany and from abroad and should be fluent in English. Applicants are required to have graduated above average at a Master level or equivalent by the time of their application. They should have a background in cell biology or immunology with experimental experience in protein biochemistry and/or molecular biology and the willingness to also work with mice.
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*Our offer*

Starting as of February 1st, 2021 or to a mutually convenient date, we offer a PhD position for one year with the possibility for two further years under the supervision of Prof. Dr. Sebastian Kobold and Dr. Bruno Cadilha. Besides the experimental work towards the PhD degree the doctorate program involves a structured training program with weekly seminars, lectures given by internationally recognized speakers, hands-on methods courses, annual research retreats as well as soft skill seminars. The salary is based on the German public service scale (TV-L, 65 %). In addition we offer further education and training, company pension scheme, childcare services, job ticket, discounts and staff accommodation.

Disabled persons will be preferentially considered in case of equal qualification. Presentation costs cannot be refunded. For further information please contact Katharina Dennemarck, e-mail: katharina.dennemarck@med.uni-muenchen.de .

Please submit your application including a CV and motivational letter.
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LMU Klinikum – Campus Innenstadt<br>
Katharina Dennemarck<br>
Lindwurnstraße 2a, 80337 Munich, Germany


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