PhD Position - Optimization of 3D Devices for In Vitro and In Vivo Applications

Your Job:

Neuronal model systems such as 2D and 3D cell cultures, brain organoids, and brain slices can physiologically mimic the brain, but require advanced electrophysiological measurement technologies to achieve long-term stable 3D recordings with single cell and millisecond space-time resolution to achieve an understanding of the function of such systems. While planar electrodes have been widely used, there are few approaches that focus on 3D geometries. Moreover, 3D microstructures help to support the organization of neuronal tissue at the single cell level, opening new avenues to physiologically relevant in vitro models. At our institute, we are developing methods to study three-dimensional neuronal networks at the level of single cells, whole networks and tissues. To this end, highly complex 3D structures are used to further improve the signal derivation of 3D nervous systems and to address important topics in life science research such as 3D network analysis, tissue engineering and organoid engineering.
Within IBI-3, we offer a PhD project aimed at improving already developed three-dimensional devices for in vitro and in vivo applications. New biomaterial combinations and geometries need to be tested to optimize the devices for their specific requirements such as electrical coupling, biocompatibility, flexibility and biodegradability.

Your tasks will include:

• Get familiar with the high precision 3D printer located in the 1000 m² ISO 1-3 Clean Room facility of FZJ
  
• Optimization of biomaterials selection and 3D printed geometries
  
• Design, fabrication, application and characterization of new optimized 3D devices for in vitro and in vivo applications

Your Profile:

• Master’s degree (or equivalent) in materials science, physics, chemistry, electrical engineering, or a related field
  
• Ability to communicate with scientists and technicians from various disciplines
  
• Well-structured and systematic research approach
  
• Passion for science
  
• Independent and analytical way of working
  
• Advantageous, yet not mandatory, are experiences of using CAD software like CATIA / INVENTOR as well as programming knowledge in PYTHON / MATLAB
  
• Interests in the field of Bioelectronics and Neuroscience
  

Please feel free to apply for the position even if you do not have all the required skills and knowledge. We may be able to teach you missing skills during your induction.

Our Offer:

We work on the very latest issues that impact our society and are offering you the chance to actively help in shaping the change! We offer ideal conditions for you to complete your doctoral degree:

• Employment with one of Germany`s top 10 employers according to Glassdoor
  
• A pleasant working environment within a highly motivated and competent working group as well as an international and interdisciplinary team at one of the most prestigious research facilities in Europe
  
• You will be supported by outstanding scientific and technical infrastructure as well as closely scientific mentoring
  
• Flexible working hours as well as a reasonable remuneration
  
• Ideal conditions for gaining practical experience alongside your studies
  
• Excellent technical equipment and the newest technology
  
• The chance to independently prepare and work on your tasks
  
• Further development of your personal strengths, e.g. through an extensive range of training courses; a structured program of continuing education and networking opportunities specifically for doctoral researchers via JuDocS, the Jülich Center for Doctoral Researchers and Supervisors: https://www.fz-juelich.de/en/judocs
  
• Targeted services for international employees, e.g. through our International Advisory Service
  

The position is for a fixed term of 3 years. Pay in line with 65% of pay group 13 of the Collective Agreement for the Public Service (TVöD-Bund) and additionally 60 % of a monthly salary as special payment („Christmas bonus“). Further information on doctoral degrees at Forschungszentrum Jülich including our other locations is available at: https://www.fz-juelich.de/gp/Careers_Docs

We welcome applications from people with diverse backgrounds, e. g. in terms of age, gender, disability, sexual orientation / identity, and social, ethnic and religious origin. A diverse and inclusive working environment with equal opportunities in which everyone can realize their potential is important to us.