PhD Position (m/f/d) in Structural Biology of Mitochondria

Updated: 15 days ago

The research team of Hauke Hillen is looking for a PhD student (m/f/d) interested in structural and molecular biology of human mitochondria.


Our research is aimed at understanding the structure and function of molecular machineries in eukaryotic cells and organelles, with a focus on human mitochondria. These sub-cellular organelles play important and diverse roles in eukaryotic cells, and their dysfunction leads to severe disease in humans. We are particularly interested in the molecular mechanisms underlying mitochondrial gene expression, and how this process is embedded in the cellular context. To study this, we combine structural biology (single-particle cryo-electron microscopy, X-Ray crystallography and cryo-electron tomography) with biochemical, biophysical and cell biological approaches.

Our groupis located at the University Medical Center Göttingen and at the Max-Planck-Institute for Biophysical Chemistry in Göttingen, Germany. We have access to state-of-the art instrumentation for cryo-EM (including a 300 kV Titan Krios TEM, a 200 kV Glacios TEM and an Aquilos FIB-SEM), X-Ray crystallography and various modern biophysical techniques. Göttingen is a vibrant, international student town located in the center of Germany and, in addition to its university, is home to a number of renowned research institutes.

We are looking for enthusiastic, open-minded candidates who are eager to use cutting-edge cryo-electron microscopy methods to dissect mitochondrial processes from the atomic to the organellar scale. Applicants should hold a M.Sc. or equivalent degree in the life sciences or a related discipline. Previous experience in structural biology or protein biochemistry is advantageous, but not required. Fluent English language skills are required. We are a small, international group with a strong team spirit and value an open-minded and collaborative working atmosphere.

The position is fixed term and the salary will be in accordance to the German Public Sector Collective Agreement (TV-L).

Applications should consist of a single PDF containing a short statement of motivation and previous experience, a CV, and the names and contacts of at least two references and should be sent to hauke.hillen@med.uni-goettingen.de. Deadline for applications is April 30th, 2021.

For more information on our research, visit our website at https://www.mpibpc.mpg.de/hillen or contact Hauke Hillen directly for informal inquiries (hauke.hillen@med.uni-goettingen.de).


The University Medical Center Göttingen is committed to professional equality. We therefore seek to increase the proportion of under-represented genders. Applicants with disabilities and equal qualifications will be given preferential treatment.

Travel and application fees cannot be refunded or transferred.


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