The LIT - Leibniz Institute for Immunotherapy (foundation under civil law) (http://www.rcii.de/en/ ), formerly RCI – is a biomedical research center focusing on translational immunology in the fields of cancer immunotherapy, transplant rejection and autoimmunity. The objective of the LIT is to develop innovative and efficient cellular immune therapeutics in these areas. Our own GMP laboratories and close networking with University and University Hospital offer excellent opportunities for clinical translation of novel immune cell products.
The group of Prof. Philipp Beckhove at the LIT (https://www.rcii.de/en/research/departments/department-for-interventional-immunology/about/ ) is looking for a highly motivated and talentedPhD student
to pursue cutting-edge research in the field of experimental and molecular tumor immunology and genetic T cell engineering.
About the project
Our group is interested in investigating the mechanisms underlying the complex interplay between immune and malignant cells, resulting in the control and eradication of cancer. With the help of state-of-the-art methods such as long-term live cell imaging, single-cell RNA-sequencing and transcriptome analysis, and CRISPR genome editing, we aim to reveal the molecular basis of effective immune responses to malignancies. In addition, we utilize the obtained knowledge by means of genetic T cell-engineering to generate T cells that have superior anti-tumor activity.
Your task will include:
- Handling of primary human and murine immune cells
- Build on existing expertise to use and further develop CRISPR genome editing
- Using cellular methods (e.g., FACS) and functional assays (cytotoxicity assays, ELISA, chemotaxis experiments, imaging, etc.) to characterize immune cells
- Engineer T cells and test their functionality in advanced in vitro systems and/or murine disease models.
We are looking for a highly motivated individual who is enthusiastic to work in an ambitious team on a competitive project, and who fits the following profile:
- Strong interest in immunology & cancer
- Master in biology/biochemistry/molecular medicine or related fields
- Creative mind that is eager to shape the project and who wants to make an impact on immunological and biomedical research
- Experimental training in molecular biology and immunology
- Keen interest in using modern technology (i.e. CRISPR, T cell engineering, imaging, etc.)
- Excellent oral and written communication skills and team spirit
- Experience in mouse models (FELASA certificate) would be advantageous.
What we offer
Our lab offers the opportunity to work at the interface of immunology and cancer, which is one of the most exciting fields of recent biomedical research. We provide a dynamic and motivating working environment where you can foster your skills and get the opportunity to learn cutting-edge technologies such as CRISPR gene editing, T cell engineering, etc.
- An international research environment that offers exciting and diverse opportunities
- Varied field of activity
- Flat hierarchies and short decision-making processes
- A highly motivated and cooperative team
- Individual development opportunities
- Flexible working hours
- Job ticket
The remuneration is based on TV-L.
Moreover, the LIT advocates for the compatibility of family and career.
Disabled applicants (m/f/d) with equal qualifications will receive preferential treatment within the recruitment procedure. Please refer to your disability status already in your application.
Please note that expenses that may arise in the context of an eventual job interview cannot be reimbursed.
For more information, please contact Prof. Philipp Beckhove (philipp.beckhove(at)ukr.de ). We are looking forward to your detailed application. Please apply via our homepage http://www.rcii.de quoting the reference PB-2023-1.
Application deadline is June 25th, 2023.
Ph D Position In Systems Biology (1.0 Fte), University of Groningen, Netherlands, about 19 hours ago
Organisation Job description Project description: Cell growth and division are fundamental cellular processes whose proper coordination is essential for cell viability and organismal health. For t...
Ph D Student (F/M/D) On Synthetic Cell Composites For Immunotherapy, Leibniz Institute for New Materials, Germany, 13 days ago
11 Sep 2023 Job Information Organisation/Company Leibniz Institute for New Materials Research Field Biological sciences Researcher Profile First Stage Researcher (R1) Country Germany Application D...
Ph D Position In The Laboratory Of Tumor Inflammation And Angiogenesis, VIB, Belgium, 9 days ago
The Laboratory of Tumor Inflammation and Angiogenesis, headed by Prof. Massimiliano Mazzone, is embedded in an international and multi-disciplinary research environment of the VIB Center for Cance...
Ph D Position On Mechanisms Of Tumor Dormancy , University of Basel, Switzerland, about 10 hours ago
A PhD position is available in the laboratory of Professor Momo Bentires-Alj (https://bentireslab.org /) at the Department of Biomedicine (DBM) in Basel, Switzerland. The successful candidate will...
Ph D Position On Nanocomposite Hydrogels For Tissue Engineering, KU Leuven, Belgium, 27 days ago
26 Aug 2023 Job Information Organisation/Company KU Leuven Research Field Technology » Nanotechnology Researcher Profile First Stage Researcher (R1) Country Belgium Application Deadline 30 Oct 202...
Ph D Position (F/M/D) In Cell Fate Engineering And Disease Modelling , St. Anna Kinderkrebsforschung GmbH, Austria, 3 days ago
21 Sep 2023 Job Information Organisation/Company St. Anna Kinderkrebsforschung GmbH Department Children's Cancer Research Institute Research Field Medical sciences » Cancer research Researcher Pro...