PhD "Defining intestinal microbiota orchestrating immune tolerance to intervene with allergic reactions to food and beyond" at Klinikum Rechts der Isar, within the Collaborative Research Centre (CRC) 1371

10.01.2023, Wissenschaftliches Personal

The gut microbiome plays a fundamental role in health and disease. CRC 1371 (Speaker Prof. Dr. Dirk Haller) focuses on the digestive tract and proposes an interdisciplinary approach to elucidate the functional relevance of microbiome signatures in the context of inflammation and cancer. Within CRC 1371, the Integrated Research Training School (IRTG) provides a qualification program for PhD students containing excellent multidisciplinary training with tailor-made subject-based and soft skills courses, annual retreats, summer school, and a supervision concept. More information on the IRTG, the research projects and principal investigators are available on the CRC 1371 website.

We are offering an exciting, interdisciplinary, experimental PhD position linking immunology, microbiology and allergy research. As part of our international team, you will investigate the role of the intestinal microbiome in governing immune tolerance to food allergens using wellestablished in vivo models of food allergy and anaphylaxis as well as in vitro and ex vivo analyses
including human samples from our patient cohort. Additionally, you will determine microbiome compositions either favoring or abolishing the development of food allergy and other inflammatory diseases. Working on a highly significant scientific topic, you can deepen your knowledge in a broad range of immunological and molecular biological methods such as flow cytometry, ELISA,
real-time PCR and Western Blot as well as bioinformatic analyses of microbiome composition (16S, metagenomics) and metabolomics. Comparison of tolerant versus allergic intestinal microbiome compositions in our model as well as in humans will allow us to ultimately design ‘bacterial therapeutics’ to treat or prevent allergic diseases via modulation of the microbiome. microbiome compositions in our model as well as in humans will allow us to ultimately design ‘bacterial therapeutics’ to treat or prevent allergic diseases via modulation of the microbiome.
Required qualification
Candidates hold a Master degree (or equivalent) in biology, microbiology or molecular biology. They are open minded, active and have a good command of the English language (oral and written).
Salary and duration
Payment is according to the wage agreement of the civil service TV-L, 65% of E13 for PhD student positions and 100% of E13 for Postdoc positions. Please note that there are no additional postgraduate degree fees required for international candidates.
Application deadline
Applications will be considered until all positions are filled.
Contact person
Prof. Dr. med. Tilo Biedermann
Klinikum rechts der Isar der Technischen Universität München
Klinik und Poliklinik für Dermatologie und Allergologie am Biederstein
Biedersteiner Str. 29
80802 München
[email protected]
Application
Applicants are asked to send one pdf file to the contact person. The file includes
1. cover letter,
2. curriculum vitae,
3. copies of academic degrees and transcripts of records,
4. preferences of projects (optional),
5. contact information for at least one letter of recommendation,
6. list of publications with link for downloading (Do not include your publications in the pdf
file).
As an equal opportunity and affirmative action employer, TUM explicitly encourages applications from women as well as from all others who would bring additional diversity dimensions to the university’s research and teaching strategies. Preference will be given to disabled candidates with essentially the same qualifications.
Data Protection Information:
When you apply for a position with the Technical University of Munich (TUM), you are submitting personal information. With regard to personal information, please take note of the Datenschutzhinweise gemäß Art. 13 Datenschutz-Grundverordnung (DSGVO) zur Erhebung und Verarbeitung von personenbezogenen Daten im Rahmen Ihrer Bewerbung. (data protection information on collecting and processing personal data contained in your application in accordance with Art. 13 of the General Data Protection Regulation (GDPR)). By submitting your application, you confirm that you have acknowledged the above data protection information of
TUM.)

Data Protection Information:
When you apply for a position with the Technical University of Munich (TUM), you are submitting personal information. With regard to personal information, please take note of the Datenschutzhinweise gemäß Art. 13 Datenschutz-Grundverordnung (DSGVO) zur Erhebung und Verarbeitung von personenbezogenen Daten im Rahmen Ihrer Bewerbung. (data protection information on collecting and processing personal data contained in your application in accordance with Art. 13 of the General Data Protection Regulation (GDPR)). By submitting your application, you confirm that you have acknowledged the above data protection information of TUM.

Kontakt: [email protected]