PhD candidate in translational epigenomics (f/m/x)

Updated: 4 months ago
Location: Oldenburg Oldenburg, NIEDERSACHSEN
Deadline: 15 Feb 2023

Area of research:

PHD Thesis

Job description:

Our mission as research center: Discover personalized medical solutions for environmentally triggered diseases to promote a healthier society in a rapidly changing world.

The Helmholtz Pioneer Campus (HPC) founded and funded by Helmholtz Munich stands for the intelligent fusion of biomedical sciences, engineering and digitization. At HPC, top scientific talents from across the globe work together on the development of novel solutions that make a difference in the prevention, diagnosis and treatment of diseases.

The 3D Genome and Molecular Neuroscience group headed by Dr Boyan Bonev studies the epigenetic mechanisms of gene regulation during development. In collaboration with a major pharmaceutical company (Roche), we are exploring the use of single-cell multiomics for epigenome-based diagnostics.

Full time



Your mission
  • Perform single-cell multiome experiments to identify and validate cell-type specific enhancers
  • Map epigenome changes associated with specific cardiovascular disease in human patient samples
  • Develop and employ novel deep learning methods for data integration across epigenetic modalities
  • Independently plan, conduct and describe scientific experiments
  • Research scientific literature and prepare manuscripts for publication in peer-reviewed journals
  • Organise scientific results and present them internally and at scientific meeting

Your qualifications
  • M. Sc. in life sciences (completed or expecting to complete) with focus on epigenetics
  • Strong motivation for pursuing an ambitious research agenda
  • Creativity, excellent analytical, technical and problem solving skills
  • Experience with NGS and single-cell technologies is preferred but not required
  • Computational experience with NGS (R, shell scripting, python) – desired

What we offer you

scientific training at HELENA Graduate School work-life balance flexible working hours
30 days annual leave

career consultation home office options
company pension scheme discounted public transport ticket Munich, with its numerous lakes and its vicinity to the Alps, is considered to be one of the cities with the best quality of life worldwide. With its first-class universities and world-leading research institutions it offers an intellectually stimulating environment.

This position also provides the opportunity for you to build specialist knowledge and collect significant professional experience, both of which will help advance your scientific career.

Remuneration and social benefits are based on the collective wage agreement for public-sector employees at federal level (EG 13 50% TV EntgO Bund). In addition, there is also the possibility of granting an allowance amounting to 15% if the necessary conditions are fulfilled. The position is (initially) limited to three years, but under certain circumstances an extension can be arranged.

To promote diversity, we welcome applications from talented people regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical abilities, religion and age by February 15, 2023. Qualified applicants with physical disabilities will be given preference.
If you have obtained a university degree abroad, we require further documents from you regarding the recognition of the degree. Please request the recognition as early as possible.

Curious? If you have further questions, simply contact Dr. Boyan Bonev, 089 2180-71902, who will be happy to be of assistance.

Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Helmholtz Pioneer CampusBiomedical Center (BMC)
Großhaderner Str. 9

82152 Planegg-Martinsried

Award for excellent gender equality policy for women and men. Helmholtz Munich is particularly committed to promoting professional equality between women and men. It therefore aims to increase the proportion of the underrepresented sex in the respective field. Helmholtz Munich is part of the Helmholtz Association, Germany’s largest scientific organization. Altogether 43.000 people currently work in its 18 scientific-technical and biological-medical research centers. The Association’s annual budget amounts to around 5 billion Euros.

This research center is part of the Helmholtz Association of German Research Centers. With more than 42,000 employees and an annual budget of over € 5 billion, the Helmholtz Association is Germany’s largest scientific organisation.

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