18 Jan 2024
Job Information
- Organisation/Company
Heidelberg University- Department
Institute of Pharmacy and Molecular Biotechnology- Research Field
Chemistry » Biochemistry
Biological sciences » Biological engineering
Technology » Biotechnology
Chemistry » Organic chemistry
Biological sciences » Biology- Researcher Profile
First Stage Researcher (R1)- Country
Germany- Application Deadline
16 Feb 2024 - 00:00 (Europe/Berlin)- Type of Contract
Temporary- Job Status
Full-time- Is the job funded through the EU Research Framework Programme?
HE / ERC- Is the Job related to staff position within a Research Infrastructure?
No
Offer Description
The Sunbul research group at the Institute of Pharmacy and Molecular Biology (IPMB), Heidelberg University (Germany) invites applications for PhD and PostDoc positions, funded by ERC, in the field of Chemical Biology. The project will primarily focus on the discovery and imaging of disease-related RNA interactomes.
RNAs play a myriad of roles in cellular processes and biotechnology. Their functions are precisely mediated by interactions with other biomolecules (e.g. proteins and other RNAs). Any perturbation of these interactions can lead to serious diseases. During the past decade, we made a significant contribution to the RNA imaging toolbox by generating novel genetically-encoded fluorescence light-up aptamers (e.g. Englert et al. Nature Commun 2023; Bühler et al. Nature Chem Biol 2023; Sunbul et al. Nature Biotechnol 2021; Zhang et al. Angew. Chemie 2021; Wirth et al. JACS 2019). Using this toolbox and harnessing synthetic chemistry, biophysics, and molecular biology, we now aim to decipher and visualize disease-related RNA interactomes.
Your tasks:
Combine the power of chemistry, biology, and physics with proteomic and metabolomic analysis;
Use molecular biology, organic chemistry, biochemistry, and imaging techniques;
Accurately record, carefully analyze and present experimental data;
Drive your research project under the direct supervision of the principal investigator;
Collaborate in projects with an interdisciplinary team of doctoral students and postdocs with different backgrounds and expertise;
Engage in proposal writing and networking;
Present your research at scientific forums.
Your profile:
Master’s degree (for PhD position) or PhD degree (for PostDocs position) in organic chemistry, biochemistry, molecular biology, or any related field;
Strong interest in RNA biotechnology, RNA biochemistry, microscopy, probes and method development;
Experience in classical biochemical and molecular biology methods is an asset;
Knowledge of biochemical and bioanalytical platforms for proteomics and next-generation sequencing is an advantage;
Ability to work and collaborate in an interdisciplinary team;
Proactive, independent, and solution-oriented way of working.
Fluency in English in written and spoken language;
Good presentation and writing skills;
We offer:
A clear research topic as well as multifold training and support;
A stimulating international and interdisciplinary research environment;
Integration into a research team that is committed to delivering the highest standards of research in a fair, supportive and collaborative manner;
Research that contributes to advancing the frontiers of scientific knowledge;
Excellent research facilities at IPMB (Heidelberg University) with access to state-of-the-art tools and infrastructure;
The opportunity to present your data at national and international conferences and participate in workshops.
Application details:
The deadline for the application is February 15, 2024. The application package including
Cover letter (2 page maximum) that clearly states
Your research and career interests
Any previous research experience (final year projects, internship(s), summer placement(s), year in industry, etc.)
Why you want to pursue a PhD or PostDoc and why you chose the Sunbul group
Curriculum Vitae with contact details (phone and email) of two academic references
Copies of your diplomas, bachelor and master grades (only for PhD applications)
should be submitted to [email protected] as a single pdf document (no more than 5 MB). For further information on the research group please visit: https://sunbulgroup.com
About Heidelberg University and the Institute of Pharmacy and Molecular Biotechnology:
Founded in 1386, Heidelberg University, a state university of Baden-Württemberg, is Germany’s oldest university. The Institute of Pharmacy and Molecular Biotechnology within the Faculty of Biosciences is focused on the development, investigation, and application of drugs and bioactive compounds, as well as on the elucidation of molecular and cellular mechanisms of action. This research integrates experimental approaches of chemistry, molecular and cellular biology, pharmacology, bioinformatics, and pharmaceutics. Main research areas of our institute include nucleic acids as tools and drug targets, development of new anti-infective drugs, molecular evolution & proteomics, research on neurodegenerative diseases, systems biology as well as drug targeting and transport.
Heidelberg University stands for equal opportunities and diversity. Qualified female candidates are especially invited to apply. Disabled persons will be given preference if they are equally qualified.
Requirements
- Research Field
- Chemistry » Biochemistry
- Education Level
- Master Degree or equivalent
Additional Information
- Website for additional job details
https://sunbulgroup.com/
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- Heidelberg University
- Country
- Germany
- Geofield
Where to apply
[email protected]
Contact
- State/Province
BW- City
Heidelberg- Website
https://www.ipmb.uni-heidelberg.de/index_en.html- Street
Im Neuenheimer Feld 364- Postal Code
69120
STATUS: EXPIRED
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