1 PhD Position in �Optimal design considerations for batch diafiltration�

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1 PhD Position in �Optimal design considerations for batch diafiltration�
Job Offer Details
Job Description

Membrane technology has become a dignified separation technology over the last decades. Numerous membrane-based separation processes established and run, to various degrees, often at least effectively. Membrane filtration processes are usually designed to fulfill dual objectives: (i) to separate certain solutes from the process liquor and (ii) to concentrate the purified solution in order to obtain a final product. In this project we aim at studying diafiltration processes that meet these simultaneous objectives. Diafiltration is a membrane-assisted process that is designed to achieve the twin-objectives of concentrating and purifying a multi-solute system according to a specific wash-water utilization strategy. Diafiltration problems arise in many applications in the food and beverage, chemical, pharmaceutical, and biotechnology sector. We can distinguish between discontinuous (i.e. batch) and continuous diafiltration. This research addresses the issue of developing efficient membrane filtration schemes for batch and continuous diafiltration processes and, in particular, deals with industrially-relevant multi-component process streams. Within the frame of this project, the most relevant issues to be addressed are: (i) to provide robust data-driven models for the diafiltration of multi- component systems where the permeation of individual components are highly interrelated, (ii) to determine optimal control of batch diafiltration by employing optimal control theory and dynamic optimization methods, and (iii) to develop a mathematical framework for the design of continuous co- and counter-current diafiltration processes. The experimental investigations focus on various industrially-relevant problems, for instance, desalination of whey with nanofiltration, concentration and purification of virus suspensions, and ultrafiltration of human serum albumin.

Full Doctorate

Research Stay

Paid position?


36 months

Working Language
English, German

Language of the Doctoral Thesis
English, German

Requirements for Applicant

Subject Requirements (Qualification)

Type of Persons
PhD student

Compulsory Attachments

  • Curriculum vitae
  • Copy of university degree
  • Letter of motivation
  • Language Certificate English

University / Organisation advertising the position

University / Organisation
Justus-Liebig-Universit�t Gie�en
35390 Gie�en

Faculty / Institute
International Giessen Graduate School for the Life Sciences (GGL)

Supervisor of the Doctoral Thesis
Herr Prof. Dr. Peter Czermak

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